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3D Dendrite Spine Detection - A Supervoxel Based Approach

  • César Antonio Ortiz
  • Consuelo Gonzalo-Martí
  • José Maria Peña
  • Ernestina Menasalvas
Part of the Lecture Notes in Computer Science book series (LNCS, volume 8537)

Abstract

In neurobiology, the identification and reconstruction of dendritic spines from large microscopy image datasets is an important tool for the study of neuronal functions and biophysical properties. But the problem of how to automatically and accurately detect and analyse structural information from dendrites images in 3D confocal microscopy has not been completely solved. We propose an novel approach to detect and extract dendritic spines regardless their size o type, for images stacks result of 3D confocal microscopy. This method is based on supervoxel segmentation and their classification using a number of different, complementary algorithms.

Keywords

segmentation supervoxels dendrite dendritic spine 

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Copyright information

© Springer International Publishing Switzerland 2014

Authors and Affiliations

  • César Antonio Ortiz
    • 1
  • Consuelo Gonzalo-Martí
    • 1
  • José Maria Peña
    • 2
  • Ernestina Menasalvas
    • 1
  1. 1.Centro de Tecnología BiomédicaUniversidad Politécnica de MadridMadridSpain
  2. 2.Departamento de Arquitectura y Tecnología de Sistemas InformáticosUniversidad Politécnica de MadridMadridSpain

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