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Pharmaceutical preparations

  • Jeremija Lj. Rašić
  • Joseph A. Kurmann
Chapter
Part of the Experientia Supplementum book series (EXS, volume 39)

Abstract

The manufacture of a dry pharmaceutical preparation containing sufficient number of viable bifidobacteria was dependent upon advances in the technique of bacterial cultivation, the knowledge of the physiological-therapeutical significance for humans and animals, as well as advances in the technique of drying. Some important milestones to this were:
  1. 1956

    Töpfer, GmbH., Dietmannsried, W. Germany, introduced on the market the first bifidobacteria preparation EUGALAN in powder form for the regeneration of the gut flora (Töpfer, GmbH, 1980).

     
  2. 1962

    As a result of work reported by Kludas (1959 b), Med. J. Carl Pflüger, Berlin, W. Germany introduced on the market a freeze — dried preparation containing bifidobacteria for the regeneration of the gut flora (Süss, 1977; Med. J. Carl Pflüger, 1980).

     
  3. 1964

    Töpfer, GmbH, Dietmannsried, W. Germany, introduced on the market the first infants preparation containing bifidobacteria LACTANA B-milk). The preparation represented a further development of the basic work of Mayer in 1948 (Töpfer, GmbH, 1980).

     
  4. 1968

    Nisshin Flour Milling Co. Ltd., Tokyo, Japan: Probably the first utilization of animal strains and first commercial bifidobacteria preparation for veterinary use (Kobayashi, 1980).

     

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Copyright information

© Springer Basel AG 1983

Authors and Affiliations

  • Jeremija Lj. Rašić
    • 1
  • Joseph A. Kurmann
    • 2
  1. 1.Food Research InstituteNovi SadYugoslavia
  2. 2.Agricultural InstituteGrangeneuve-FribourgSwitzerland

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