• João P. BelfoEmail author
  • João M. Lemos
Part of the SpringerBriefs in Electrical and Computer Engineering book series (BRIEFSELECTRIC)


This chapter motivates the study of Optimal Impulsive Control (OIC) applied to cancer therapy. The OIC problem is formulated and divided in three control sub-problems that are treated in detail in Chap.  5. The model structure used, that comprises pharmacokinetics, pharmacodynamics, and tumor dynamics, is described. Relevant background literature is described.


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© The Author(s), under exclusive license to Springer Nature Switzerland AG 2021

Authors and Affiliations

  1. 1.Control of Dynamical SystemsINESC-IDLisboaPortugal

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