Assessment and Comparison of Colour Fidelity of Whole Slide Imaging Scanners

  • Norman ZerbeEmail author
  • Alexander Alekseychuk
  • Peter Hufnagl
Part of the Lecture Notes in Computer Science book series (LNCS, volume 12090)


The aim of this work is to develop a colourimetrically justified method for determination of colour fidelity of WSI scanners. We measure the absolute accuracy of colour reproduction and assess the scanner’s ability to resolve similar colours, which seems to be even more important for diagnostic and research tasks. Along this, some theoretical background is given which helps in understanding of common sources of failures in colour reproduction. The work was done in the framework of 2-nd and 3-rd International Scanner Contest. We hope this publication will be useful for scanner manufactures as well as for academical and clinical users.


Whole slide imaging Quality assurance Color calibration Digital pathology Colour target 


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Copyright information

© Springer Nature Switzerland AG 2020

Authors and Affiliations

  • Norman Zerbe
    • 1
    Email author
  • Alexander Alekseychuk
    • 2
  • Peter Hufnagl
    • 1
    • 3
  1. 1.Charité - Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Institute of PathologyBerlinGermany
  2. 2.Vision in X industrial imaging GmbHBerlinGermany
  3. 3.Center for Biomedical Image and Information Processing (CBMI)HTW University of Applied Sciences BerlinBerlinGermany

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