Biophotonic Therapy Induced Photobiomodulation

  • Deirdre Edge
  • Mikkel Schødt
  • Michael Canova Engelbrecht NielsenEmail author


Biophotonics—the interdisciplinary field marrying photonics and biology—has had a profound impact on modern medicine, supporting the diagnosis, management and treatment of disease. Learning from evolutionary mechanisms of photon absorption by chromophores coupled with our growing knowledge of light–tissue interactions has uncovered a niche area of phototherapy—photobiomodulation (PBM). PBM is the capacity of non-ionizing forms of light to induce photochemical and photophysical biological reactions. Now widely applied in various fields to restore function, stimulate and aid healing, its role in medical and cosmetic dermatology is dominating. In this chapter, we discuss the current knowledge of PBM and introduce a novel induction of PBM using fluorescent light energy (FLE). Research supports the capacity of FLE to modulate immune and connective cell function—supporting an anti-inflammatory and healing effect. It is currently used clinically as a stand-alone treatment for inflammatory skin conditions, acne vulgaris and rosacea, as well as offering adjunct support to more invasive technologies and rejuvenating the skin. Further exploration underpinning its unique mechanism of action will enlighten future dermatological practice and beyond.


Fluorescent light energy Chromophore Photobiomodulation Photobiological Absorption Anti-inflammatory Phototherapy Biophotonic Immunomodulation 


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© Springer Nature Switzerland AG 2020

Authors and Affiliations

  • Deirdre Edge
    • 1
  • Mikkel Schødt
    • 1
  • Michael Canova Engelbrecht Nielsen
    • 1
    Email author
  1. 1.Department of Research and DevelopmentFB DermatologyBallerupDenmark

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