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An Iterative Cyclic Algorithm for Designing Vaccine Distribution Networks in Low and Middle-Income Countries

  • Yuwen Yang
  • Jayant RajgopalEmail author
Conference paper
  • 14 Downloads
Part of the Lecture Notes on Multidisciplinary Industrial Engineering book series (LNMUINEN)

Abstract

The World Health Organization – Expanded Programme on Immunization (WHO-EPI) was developed to ensure that all children have access to common childhood vaccinations. Unfortunately, because of inefficient distribution networks and cost constraints, millions of children in many low and middle-income countries still go without being vaccinated. In this paper, we formulate a mathematical programming model for the design of a typical WHO-EPI network with the goal of minimizing costs while providing the opportunity for universal coverage. Since it is only possible to solve small versions of the model optimally, we describe an iterative heuristic that cycles between solving restrictions of the original problem and show that it can find very good solutions in reasonable time for larger problems that are not directly solvable.

Keywords

Vaccines Network design Mixed integer programming Heuristics 

Notes

Acknowledgement

This work was partially supported by the National Science Foundation via Award No. CMII-1536430.

References

  1. 1.
    World Health Organization – WHO: Immunization. http://www.who.int/topics/immunization/en/. Accessed 14 May 2019
  2. 2.
    Bland, J., Clements, J.: Protecting the world’s children: the story of WHO’s immunization programme. World Health Forum 19(2), 162–173 (1997)Google Scholar
  3. 3.
    GAVI: History of Gavi. http://www.gavi.org/about/mission/history. Accessed 14 May 2019
  4. 4.
    World Health Organization – WHO: The Expanded Programme on Immunization. http://www.who.int/immunization/programmes_systems/supply_chain/benefits_of_immunization/en/. Accessed 14 May 2019
  5. 5.
    World Health Organization – WHO: Immunization coverage. http://www.who.int/news-room/fact-sheets/detail/immunization-coverage. Accessed 14 May 2019
  6. 6.
    Gavi: Gavi progress reports, global vaccine alliance. https://www.gavi.org/progress-report/. Accessed 14 May 2019
  7. 7.
    Yadav, P., Lydon, P., Oswald, J., Dicko, M., Zaffran, M.: Integration of vaccine supply chains with other health commodity supply chains: a framework for decision making. Vaccine 32(50), 6725–6732 (2014)CrossRefGoogle Scholar
  8. 8.
    World Health Organization – WHO: Prequalified devices and equipment. http://apps.who.int/immunization_standards/vaccine_quality/pqs_catalogue/categorylist.aspx?cat_type=device. Accessed 14 May 2019
  9. 9.
    Melkote, S., Daskin, M.S.: Capacitated facility location/network design problems. Eur. J. Oper. Res. 129(3), 481–495 (2001)MathSciNetCrossRefGoogle Scholar
  10. 10.
    Şahin, G., Süral, H.: A review of hierarchical facility location models. Comput. Oper. Res. 34(8), 2310–2331 (2007)MathSciNetCrossRefGoogle Scholar
  11. 11.
    Melo, T.M., Nickel, S., Saldanha-Da-Gama, F.: Facility location and supply chain management – a review. Eur. J. Oper. Res. 196(2), 401–412 (2009)MathSciNetCrossRefGoogle Scholar
  12. 12.
    Chen, S.-I., Norman, B.A., Rajgopal, J., Assi, T.M., Lee, B.Y., Brown, S.T.: A planning model for the WHO-EPI vaccine distribution network in developing countries. IIE Trans. 46(8), 853–865 (2014)CrossRefGoogle Scholar
  13. 13.
    Lim, J., Norman, B.A., Rajgopal, J.: Redesign of vaccine distribution networks. Int. Trans. in Oper. Res. (2019, in press).  https://doi.org/10.1111/itor.12758

Copyright information

© Springer Nature Switzerland AG 2020

Authors and Affiliations

  1. 1.Department of Industrial EngineeringUniversity of PittsburghPittsburghUSA

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