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Assessment of Urinary 1-hydroxypyrene and 3-hydroxybenzo(a)pyrene in Barbecue Grill Workers

  • Marta Oliveira
  • Sílvia Capelas
  • Cristina Delerue-Matos
  • Isabel Brás Pereira
  • Simone MoraisEmail author
Chapter
  • 116 Downloads
Part of the Studies in Systems, Decision and Control book series (SSDC, volume 277)

Abstract

Cooks and kitchen workers at restaurants are continuously exposed to cooking fumes released during food processing. There is limited information about kitchen and barbecue grill workers’ occupational exposure. This work determined the levels of 1-hydroxypyrene and 3-hydroxybenzo(a)pyrene in the post-shift urines of barbecue grill workers during a regular working period. Levels of both polycyclic aromatic hydrocarbon (PAH) metabolites were extracted by solid-phase extraction and quantified by high-performance liquid chromatography with fluorescence detection. Overall, median concentrations of 1-hydroxypyrene were significantly higher during the period when workers were exposed than in the days out of duty (0.068 versus 0.050 µmol/mol creatinine; p = 0.003). Total exposure to 1-hydroxypyrene was well below the benchmark level of 0.5 µmol/mol creatinine proposed by the American Conference of Governmental Industrial Hygienists. The PAH biomarker of exposure to carcinogens, 3-hydroxybenzo(a)pyrene, was only detected during the working period (0.123–2.07 nmol/mol creatinine). Findings achieved in this study suggest that grill workers are occupationally exposed to PAHs and thus are more vulnerable to the potential health risks associated with long-term exposures. However, more studies are needed with other biomarkers of exposure to PAHs to better estimate the occupational exposure of barbecue grill workers.

Keywords

Human biomonitoring Occupational exposure Urinary monohydroxyl metabolites 

Notes

Acknowledgements

This work was financially supported by European (FEDER funds through COMPETE) and National funds through Fundação para a Ciência e Tecnologia project UID/QUI/50006/2019. M. Oliveira thanks to FCT/MCTES for the CEEC Individual 2017 Program Contract: CEECIND/03666/2017. Authors are thankful to all barbecue grill workers that participated in this study.

References

  1. 1.
    Abdel-Shafy, H.I., Mansour, M.S.M.: A review on polycyclic aromatic hydrocarbons: Source, environmental impact, effect on human health and remediation. Egyptian J. Petroleum 25, 107–123 (2016)CrossRefGoogle Scholar
  2. 2.
    USEPA.: Guidelines for Carcinogen Risk Assessment, EPA/630/P-03/001F, Risk Assessment Forum. US Environmental Protection Agency, Washington, D.C. (2005)Google Scholar
  3. 3.
    IARC.: Monographs on the Evaluation of the Carcinogenic Risks to Humans: Some Non-Heterocyclic Polycyclic Aromatic Hydrocarbons and Some Related Exposures, pp. 1–853. International Agency for Research on Cancer (2010)Google Scholar
  4. 4.
    IARC.: Monographs on the Evaluation of the Carcinogenic Risks to Humans: Naphthalene. International Agency for Research on Cancer, Lyon, France (2002)Google Scholar
  5. 5.
    Kamal, A., Cincinelli, A., Martellini, T., Malik, R.N.: A review of PAH exposure from the combustion of biomass fuel and their less surveyed effect on the blood parameters. Environ. Sci. Pollut. Res. 22, 4076–4098 (2015)CrossRefGoogle Scholar
  6. 6.
    Oliveira, M., Slezakova, K., Delerue-Matos, C., Pereira, M.C., Morais, S.: Children environmental exposure to particulate matter and polycyclic aromatic hydrocarbons and biomonitoring in school environments: a review on indoor and outdoor exposure levels, major sources and health impacts. Environ. Int. 124, 180–204 (2019)CrossRefGoogle Scholar
  7. 7.
    Gao, P., da Silva, E., Hou, L., Denslow, N.D., Xiang, P., Ma, L.Q.: Human exposure to polycyclic aromatic hydrocarbons: Metabolomics perspective. Environ. Int. 119, 466–477 (2018)CrossRefGoogle Scholar
  8. 8.
    Moustafa, G.A., Xanthopoulou, E., Riza, E., Linos, A.: Skin disease after occupational dermal exposure to coal tar: a review of the scientific literature. Int. J. Dermatol. 54, 868–879 (2015)CrossRefGoogle Scholar
  9. 9.
    Taner, S., Pekey, B., Pekey, H.: Fine particulate matter in the indoor air of barbeque restaurants: elemental compositions, sources and health risks. Sci. Total Environ. 454, 79–87 (2013)CrossRefGoogle Scholar
  10. 10.
    Huang, H.L., Lee, W.M.G., Wu, F.S.: Emissions of air pollutants from indoor charcoal barbecue. J. Hazard. Mater. 302, 198–207 (2016)CrossRefGoogle Scholar
  11. 11.
    Kim, H.J., Chung, Y.K., Kwak, K.M., Ahn, S.J., Kim, Y.H., Ju, Y.S., Kwon, Y.J., Kim, E.A.: Carbon monoxide poisoning-induced cardiomyopathy from charcoal at a barbecue restaurant: a case report. Ann. Occup. Environ. Med. 27, 8 (2015)CrossRefGoogle Scholar
  12. 12.
    Kuo, C.Y., Chang, S.H., Chien, Y.C., Chiang, F.Y., Wei, Y.C.: Exposure to carcinogenic PAHs for the vendors of broiled food. J. Expo. Sci. Environ. Epidemiol. 16, 410–416 (2006)CrossRefGoogle Scholar
  13. 13.
    Li, Y.C., Shu, M., Ho, S.S.H., Wang, C., Cao, J.J., Wang, G.H., Wang, X.X., Wang, K., Zhao, X.Q.: Characteristics of PM2.5 emitted from different cooking activities in China. Atmos. Res. 166, 83–91 (2015)Google Scholar
  14. 14.
    Song, Y.F., Sun, L., Wang, X.F., Zhang, Y.T., Wang, H., Li, R., Xue, L.K., Chen, J.M., Wang, W.X.: Pollution characteristics of particulate matters emitted from outdoor barbecue cooking in urban Jinan in eastern China. Front. Env. Sci. Eng. 12, 8 (2018)Google Scholar
  15. 15.
    Wu, C.C., Bao, L.J., Guo, Y., Li, S.M., Zeng, E.Y.: Barbecue fumes: an overlooked source of health hazards in outdoor settings? Environ. Sci. Technol. 49, 10607–10615 (2015)CrossRefGoogle Scholar
  16. 16.
    Oliveira, M., Capelas, S., Delerue-Matos, C., Pereira, I.B., Morais, S.: Barbecue grill workers occupational exposure to particulate-bound polycyclic aromatic hydrocarbons. In: Arezes, P.M., Baptista, J.S., Barroso, M.P., Carneiro, P., Cordeiro, P., Costa, N., Melo, R.B., Miguel, A.S., Perestrelo, G. (eds.) Occupational and Environmental Safety and Health, pp. 201–209. Springer International Publishing, Cham (2019)CrossRefGoogle Scholar
  17. 17.
    Acharya, N., Gautam, B., Subbiah, S., Rogge, M.M., Anderson, T.A., Gao, W.M.: Polycyclic aromatic hydrocarbons in breast milk of obese vs normal women: Infant exposure and risk assessment. Sci. Total Environ. 668, 658–667 (2019)CrossRefGoogle Scholar
  18. 18.
    Ke, Y.B., Huang, L.H., Xia, J.J., Xu, X.Y., Liu, H.H., Li, Y.R.: Comparative study of oxidative stress biomarkers in urine of cooks exposed to three types of cooking-related particles. Toxicol. Lett. 255, 36–42 (2016)CrossRefGoogle Scholar
  19. 19.
    Ke, Y.B., Cheng, J.Q., Zhang, Z.C., Zhang, R.L., Zhang, Z.Z., Shuai, Z.H., Wu, T.C.: Increased levels of oxidative DNA damage attributable to cooking-oil fumes exposure among cooks. Inhal. Toxicol. 21, 682 (2009)CrossRefGoogle Scholar
  20. 20.
    Lai, C.H., Jaakkola, J.J.K., Chuang, C.Y., Liou, S.H., Lung, S.C., Loh, C.H., Yu, D.S., Strickland, P.T.: Exposure to cooking oil fumes and oxidative damages: a longitudinal study in Chinese military cooks. J. Expo. Sci. Environ. Epidemiol. 23, 94–100 (2013)CrossRefGoogle Scholar
  21. 21.
    Pan, C.H., Chan, C.C., Wu, K.Y.: Effects on Chinese restaurant workers of exposure to cooking oil fumes: a cautionary note on urinary 8-hydroxy-2′-deoxyguanosine. Cancer Epidemiol. Biomark. Prev. 18, 687–687 (2009)CrossRefGoogle Scholar
  22. 22.
    Pan, C.H., Chan, C.C., Huang, Y.L., Wu, K.Y.: Urinary 1-hydroxypyrene and malondialdehyde in male workers in Chinese restaurants. Occup. Environ. Med. 65, 732–735 (2008)CrossRefGoogle Scholar
  23. 23.
    Singh, A., Nair, K.C., Kamal, R., Bihari, V., Gupta, M.K., Mudiam, M.K.R., Satyanarayana, G.N.V., Raj, A., Haq, I., Shukla, N.K., Khan, A.H., Srivastava, A.K.: Assessing hazardous risks of indoor airborne polycyclic aromatic hydrocarbons in the kitchen and its association with lung functions and urinary PAH metabolites in kitchen workers. Clin. Chim. Acta 468, 231–232 (2017)CrossRefGoogle Scholar
  24. 24.
    Wang, J.J., Luo, X.L., Xu, B., Wei, J., Zhang, Z.Z., Zhu, H.L.: Elevated oxidative damage in kitchen workers in chinese restaurants. J. Occup. Health 53, 327–333 (2011)CrossRefGoogle Scholar
  25. 25.
    WHO.: World Health Survey B—Individual Questionnaire. Evidence and Information Policy (2002)Google Scholar
  26. 26.
    Oliveira, M., Slezakova, K., Alves, M.J., Fernandes, A., Teixeira, J.P., Delerue-Matos, C., Pereira, M.D., Morais, S.: Firefighters’ exposure biomonitoring: impact of firefighting activities on levels of urinary monohydroxyl metabolites. Int. J. Hyg. Environ. Health 219, 857–866 (2016)CrossRefGoogle Scholar
  27. 27.
    Miller, J.C., Miller, M.J.N.: Statistics for Analytical Chemistry. Pearson Education Ltd, Harlow (2000)zbMATHGoogle Scholar
  28. 28.
    Kanagasabapathy, S.K.A.S.: Guidelines on standard operating procedures for clinical Chemistry, pp. 25–28. World Health Organization. Regional Office for South-East Asia, New Delhi (2000)Google Scholar
  29. 29.
    WHO.: Biological Monitoring of Chemical Exposure in Workplace-Guidelines. World Health Organization, Geneva (1996)Google Scholar
  30. 30.
    ACGIH.: Documentation for a Recommended BEI of Polycyclic AromaticHydrocarbons. In: American Conference of Governmental Industrial Hygienists, Cincinatti, Ohio, USA (2010)Google Scholar
  31. 31.
    Dai, W.T., Zhong, H.B., Li, L.J., Cao, J.J., Huang, Y., Shen, M.X., Wang, L.Q., Dong, J.G., Tie, X.X., Ho, S.S.H., Ho, K.F.: Characterization and health risk assessment of airborne pollutants in commercial restaurants in northwestern China: under a low ventilation condition in wintertime. Sci. Total Environ. 633, 308–316 (2018)CrossRefGoogle Scholar

Copyright information

© Springer Nature Switzerland AG 2020

Authors and Affiliations

  • Marta Oliveira
    • 1
  • Sílvia Capelas
    • 1
    • 2
  • Cristina Delerue-Matos
    • 1
  • Isabel Brás Pereira
    • 3
  • Simone Morais
    • 1
    Email author
  1. 1.REQUIMTE-LAQV, Instituto Superior de Engenharia do PortoPortoPortugal
  2. 2.Ibero Massa FlorestalOliveira de AzeméisPortugal
  3. 3.CIETI-Instituto Superior de Engenharia do PortoPortoPortugal

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