Bone Quality Assessment at the Atomic Scale

  • J. M. D. A. RolloEmail author
  • R. S. Boffa
  • R. Cesar
  • R. Erbereli
  • D. C. Schwab
  • T. P. Leivas
Part of the Lecture Notes in Computational Vision and Biomechanics book series (LNCVB, volume 35)


The assessment of osteoporosis regarding bone mass and microarchitecture “quality” contributes in determining fracture risk. Therefore, the crystalline structure of hydroxyapatite may indicate the quality of trabecular bones through the identification of crystallite sizes, microhardness and microdeformation values and calcium and phosphorous proportions in the three types of bones: normal, osteopenic, and osteoporotic. Nine L1 vertebrae-dried trabecular bones from human cadavers were used. The characterization of the three types of bones was made through scanning electron microscopy, EDS, microhardness, and X-ray diffractometry with the Rietveld refinement method. The results show that the microstructural characterization possibilities the identification of the three types of bones: normal, osteopenic, and osteoporotic, allowing the detection of osteoporosis based on bone quality.


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© Springer Nature Switzerland AG 2020

Authors and Affiliations

  • J. M. D. A. Rollo
    • 1
    Email author
  • R. S. Boffa
    • 1
  • R. Cesar
    • 2
  • R. Erbereli
    • 2
  • D. C. Schwab
    • 3
  • T. P. Leivas
    • 4
  1. 1.Departamento de Engenharia de MateriaisUniversidade de São Paulo (USP), Escola de Engenharia de São CarlosSão CarlosBrazil
  2. 2.Departamento de Engenharia MecânicaUniversidade de São Paulo (USP), Escola de Engenharia de São CarlosSão CarlosBrazil
  3. 3.DCS - English Consultancy ServicesSão CarlosBrazil
  4. 4.Instituto de Ortopedia E TraumatologiaHCFMUSP-OIT—Hospital de Clinicas da Faculdade de Medicina, Universidade de São Paulo (USP)São PauloBrazil

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