Antioxidants, Therapeutic Options, and Regulation of the Immune Responses

Part of the Nanomedicine and Nanotoxicology book series (NANOMED)


The European Cooperation in Science and Technology (COST) provides an ideal framework to establish multidisciplinary research networks. COST Action BM1203 (EU-ROS) represents a consortium of researchers from different disciplines who are dedicated to providing new insights and tools for better understanding redox biology and medicine and, in the long run, to finding new therapeutic strategies to target dysregulated redox processes in various diseases. This chapter highlights the major achievements of EU-ROS as well as research updates and new perspectives arising from its members. The formation of reactive oxygen and nitrogen species (RONS) is an established hallmark of our aerobic environment and metabolism but RONS also acts as messengers via redox regulation of essential cellular processes. The fact that many diseases have been found to be associated with oxidative stress established the theory of oxidative stress as a trigger of diseases that can be corrected by antioxidant therapy. However, while experimental studies support this thesis, clinical studies still generate controversial results, due to the complex pathophysiology of oxidative stress in humans.


ABCA1 ABCG1 HDL transporters Cholesterol efflux Immune responses Antioxidants Redox therapeutics Inflammation Oxidative stress 


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© Springer Nature Switzerland AG 2020

Authors and Affiliations

  1. 1.Physical Chemistry and Nanoscience, Department of Chemistry, Faculty of ScienceAl Baha UniversityBaljurashiSaudi Arabia

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