Spongiotic and Psoriasiform Dermatitis

  • María Teresa Fernández-FiguerasEmail author
  • Luis Puig


The histopathological diagnosis of spongiotic and psoriasiform dermatitis is often challenging. There is a significant histologic overlap among different diseases, unusual lesions are those most frequently biopsied, and correlation with the clinical presentation is mandatory to establish the final diagnosis.

Spongiosis is the hallmark of nummular dermatitis, atopic dermatitis, allergic and irritant contact dermatitis, dyshidrotic dermatitis, xerotic eczema, id reaction, photoallergic reaction, lichen simplex chronicus, and prurigo nodularis. These entities are often grouped under the name of eczema. Spongiosis is also a constant feature in pityriasis rosea and can be a superimposed feature in a wide range of inflammatory and neoplastic processes.

Psoriasiform dermatitis is characterized by regular undulating acanthosis often with parakeratosis and intracorneal abscesses of neutrophils. Psoriasis is the prototype of this histologic pattern that is shared with seborrheic dermatitis, pityriasis rubra pilaris, and pityriasis lichenoides chronica.


Spongiosis Eczema Dermatitis Atopy Contact Psoriasis Psoriasiform Seborrheic Pityriasis 



Clinical pictures for case study 3 were provided by Dr. Juan Antonio Moreno Romero, Department of Dermatology, Hospital Universitari General de Catalunya. Sant Cugat. Barcelona.


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Authors and Affiliations

  1. 1.Universitat International de Catalunua, Department of Surgical PathologyHospital Universitari General de CatalunyaBarcelonaSpain
  2. 2.Department of DermatologyHospital Santa Creu i Sant Pau, Universitat Autònoma de BarcelonaBarcelonaSpain

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