Additive Manufacturing and Nanotherapeutics: Present Status and Future Perspectives in Wound Healing
In the past decades, additive manufacturing had emerged as a cost-effective and clinically acceptable means for fabrication of diverse and biologically compatible materials of complex geometrical structure. This technology can use an array of materials (mainly biopolymers) as carriers, which can print the incorporated cells, drug, or even nanoparticles in desired shape with high accuracy and precision.
In this chapter, we have highlighted the current status and the future scope of fabricating the tailor-made nanotherapeutics and additive manufacturing techniques for effective wound healing. Current market demand of the tailor-made wound dressings/implants has contributed positively towards the use of additive manufacturing in their fabrication as it can address specific problems associated with various phases (namely hemostasis, inflammation, proliferation, and remodeling) of wound healing phenomenon. Additive manufacturing fabricated materials can either work as carriers for nanostructured therapeutic agents like silver nanoparticles, nanoparticle loaded antibiotics and antioxidants or they can print biomaterials (with or without drug) in complex nanoporous scaffolds.
KeywordsNanotherapeutics Additive manufacturing Wound healing Nanomaterials 3D scaffolds
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