Microelectrode Recording in Neurosurgical Patients

  • Bornali Kundu
  • Andrea A. Brock
  • John A. Thompson
  • John D. RolstonEmail author


Microelectrode recording (MER) is used to localize and map deep brain structures during neurosurgical procedures and has been a fruitful technique in human neuroscience research. In this chapter, we briefly review the biophysical principles of MER, discuss the use of the technique for targeting as it relates to movement disorders, and conclude with a comparison of the accuracy obtained with MER and with direct targeting with imaging.


Microelectrode recording Parkinson disease Single-unit recording Local field potentials Movement disorders Dystonia Globus pallidus Subthalamic nucleus Ventral intermediate nucleus 



Anterior commissure–posterior commissure


Computed tomography


Deep brain stimulation


Digital signal processing




Globus pallidus externus


Globus pallidus internus


Local field potential


Microelectrode recording


Magnetic resonance imaging


Parkinson disease


Substantia nigra pars reticulate


Subthalamic nucleus


Unified Parkinson’s Disease Rating Scale




Ventral intermediate nucleus of the thalamus


Ventralis oralis anterior


Ventralis oralis posterior


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Copyright information

© Springer Nature Switzerland AG 2020

Authors and Affiliations

  • Bornali Kundu
    • 1
  • Andrea A. Brock
    • 1
  • John A. Thompson
    • 2
  • John D. Rolston
    • 1
    • 3
    Email author
  1. 1.Department of Neurosurgery, Clinical Neurosciences CenterUniversity of UtahSalt Lake CityUSA
  2. 2.Department of NeurosurgeryUniversity of Colorado School of MedicineAuroraUSA
  3. 3.Department of Biomedical EngineeringUniversity of UtahSalt Lake CityUSA

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