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Gastrointestinal and Hepatic Issues in Women with Turner Syndrome

  • Ghassan T. WahbehEmail author
  • Amanda Bradshaw
  • Lauren White
  • Dale Lee
Chapter
  • 21 Downloads

Abstract

Patients with Turner syndrome are more prone than the general population to develop gastrointestinal inflammatory and noninflammatory conditions. Among the inflammatory condition with significant impact on growth, development, and quality of life are celiac disease and Crohn’s disease. Additionally both conditions may impact the response to hormonal therapy in TS if untreated. It is imperative to recognize the presence of celiac disease and Crohn’s disease early, despite the diagnostic challenge since the presenting signs and symptoms often overlap with TS manifestation including growth delay and amenorrhea. Among the noninflammatory manifestations are gastrointestinal bleeding and hepatic manifestations. Bleeding can be life-threatening and warrants emergent care. A multidisciplinary team approach is often needed to address such gastrointestinal manifestations to optimize patient outcomes. This chapter provides a review of the relevant gastrointestinal manifestations in individuals with TS.

Keywords

Turner Celiac Crohn’s Gastrointestinal bleeding Vascular malformation 

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Copyright information

© Springer Nature Switzerland AG 2020

Authors and Affiliations

  • Ghassan T. Wahbeh
    • 1
    Email author
  • Amanda Bradshaw
    • 2
  • Lauren White
    • 2
  • Dale Lee
    • 3
  1. 1.Pediatrics-Gastroenterology, Inflammatory Bowel Disease CenterSeattle Children’s Hospital, University of WashingtonSeattleUSA
  2. 2.GastroenterologySeattle Children’s HospitalSeattleUSA
  3. 3.Pediatrics-Gastroenterology, Clinical Nutrition & Celiac ProgramSeattle Children’s Hospital, University of WashingtonSeattleUSA

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