Structural Equation Modeling (SEM) with SPSS Analysis of Moment Structures (Amos) Software for Cause Effect Relationships in Pharmacodynamic Studies I (35 Patients)

  • Ton J. Cleophas
  • Aeilko H. Zwinderman


This chapter is to assess, whether the Amos (analysis of moment structures) add-on module of SPSS statistical software, frequently used in econo-/sociometry, but little used in medicine, is able to perform an SEM (structural equation modeling) analysis of pharmacodynamic data.

Supplementary material

333106_2_En_49_MOESM1_ESM.sav (1 kb)
amos1 (SAV 1 kb)

Copyright information

© Springer Nature Switzerland AG 2020

Authors and Affiliations

  • Ton J. Cleophas
    • 1
  • Aeilko H. Zwinderman
    • 2
  1. 1.Department Medicine Albert Schweitzer HospitalDordrechtThe Netherlands
  2. 2.Academic Medical CenterDepartment Biostatistics and EpidemiologyAmsterdamThe Netherlands

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