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Eosinophilic Esophagitis

  • Carla PerezEmail author
  • Anthony Olive
  • Carla M. Davis
Chapter
  • 56 Downloads

Abstract

Eosinophilic esophagitis (EoE) is a common cause of chronic esophagitis and is one of the leading causes of dysphagia and food impaction in children. EoE is defined as a chronic immune-mediated condition characterized by esophageal symptoms in the setting of eosinophilic predominant inflammation of the esophagus. While genetics and the environment have been implicated in the development of EoE, the pathogenesis still remains unknown.

If EoE is not recognized or treated, it can progress to esophageal stricture and functional abnormalities that can impair the quality of life of children. Currently, diagnosis is made by upper endoscopy with biopsy. A variety of treatment approaches are used in the care of EoE patients, including proton pump inhibitors, dietary interventions, and swallowed topical steroids. There is a plethora of research studies underway to better understand this disease and to identify new treatment modalities.

Keywords

Eosinophilic esophagitis (EoE) Esophageal stricture Endoscopy Swallowed steroids Elimination diets Dilation Proton pump inhibitors Allergy testing 

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© Springer Nature Switzerland AG 2020

Authors and Affiliations

  1. 1.Section of Gastroenterology, Hepatology and Nutrition, Department of PediatricsBaylor College of Medicine, Texas Children’s HospitalHoustonUSA
  2. 2.Section of Immunology, Allergy and Retrovirology, Department of PediatricsBaylor College of Medicine, Texas Children’s HospitalHoustonUSA

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