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Learning Human Cognition via fMRI Analysis Using 3D CNN and Graph Neural Network

  • Xiuyan NiEmail author
  • Tian Gao
  • Tingting Wu
  • Jin Fan
  • Chao Chen
Conference paper
Part of the Lecture Notes in Computer Science book series (LNCS, volume 11846)

Abstract

Human cognitive control involves how mental resources are allocated when the brain processes various information. The study of such complex brain functionality is essential in understanding different neurological disorders. To investigate cognition control, various cognitive tasks have been designed and functional MRI data have been collected. In this paper, we study uncertainty representation, an important problem in human cognition study, with task-evoked fMRI data. Our goals are to learn how brain region of interests (ROIs) are activated under tasks with different uncertainty levels and how they interact with each other. We propose a novel neural network architecture to achieve the two goals simultaneously. Our architecture uses a 3D convolutional neural network (CNN) to extract a high-level representation for each ROI, and uses a graph neural network module to capture the interactions between ROIs. Empirical evaluations reveal that our method significantly outperforms the existing methods, and the derived brain network is consistent with domain knowledge.

Keywords

Graph neural network Brain network learning 

Notes

Acknowledgement

This work was partially supported by NSF IIS-1855759 and CCF-1855760.

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Copyright information

© Springer Nature Switzerland AG 2019

Authors and Affiliations

  • Xiuyan Ni
    • 1
    Email author
  • Tian Gao
    • 2
  • Tingting Wu
    • 3
  • Jin Fan
    • 3
  • Chao Chen
    • 1
    • 4
  1. 1.Department of Computer Science, The Graduate CenterCity University of New York (CUNY)New YorkUSA
  2. 2.IBM Thomas J. Watson Research CenterYorktown HeightsUSA
  3. 3.Department of PsychologyCUNY Queens CollegeFlushingUSA
  4. 4.Department of Biomedical InformaticsStony Brook UniversityStony BrookUSA

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