Advertisement

On the Verge of Life: Looking for a New Scientific Paradigm

  • Arturo CarsettiEmail author
Chapter
Part of the Studies in Applied Philosophy, Epistemology and Rational Ethics book series (SAPERE, volume 50)

Abstract

From a general point of view, at the level of life we are constantly faced with an inner self-modulation of a very peculiar coupled system: the alternative splicing represents only one of the essential tools relative to the self-organization of the channel. In this sense, the dialectics between coder and ruler really plays a fundamental role: it is in view of a continuous synthesis of new proteins and new structures as well as of the accomplishment, each time, of a correct assimilation process. In any case, the problem is to establish, every time, a correct relationship between invariance and morphogenesis. Life is hiding in the creative equilibrium at stake, a balance that must be constantly renewed on pain of dissipating life itself. Meaning and incompressibility are the two actors who tread the scene of life determining each time the due balance in accordance with an evolution which concerns the surfacing of the natural world but in the conditions of a continuous (and “intended”) metamorphosis.

References

  1. 1.
    Gerstein, M. B., et al. (2012). Architecture of the human regulatory network derived from ENCODE data. Nature, 489, 91–100.Google Scholar
  2. 2.
    Berget, S. M., et al. (1977). Spliced segments at the 5′ adenovirus 2 late mRNA. Proceedings of National Academy of Sciences, 74, 3171–3175.Google Scholar
  3. 3.
    Darnell, J.E., Jr. (1978). Implication of RNA-RNA splicing in evolution of eukaryotic cells. Science, 202, 1257–1260.CrossRefGoogle Scholar
  4. 4.
    Schmuker, D., et al. (2000). Drosophila Dscam is an axon guidance receptor exhibiting extraordinary molecular diversity. Cell, 101, 671–684.CrossRefGoogle Scholar
  5. 5.
    Keren, H., Lev-Maor, G., & Ast, G. (2010). Alternative splicing and evolution: Diversification, exon definition and function. Nature Reviews. Genetics, 1, 345–355.Google Scholar
  6. 6.
    Carsetti, A. (2012). Eigenforms, natural computing and morphogenesis. Paper presented to the Turing Centenary Conference, CiE 2012.Google Scholar
  7. 7.
    Atlan, H. (2000). Self-organizing networks: Weak, strong and intentional, the role of their under determination. In A. Carsetti (Ed.), Functional models of cognition (pp. 127–143). Dordrecht: Kluwer A.P.CrossRefGoogle Scholar
  8. 8.
    Kourilsky, P. (1987). Les artisans de l’hérédité. Paris: O. Jacob.Google Scholar
  9. 9.
    Bray, D. (1995). Protein molecules as computational elements in living cells. Nature, 376, [p. 309].Google Scholar
  10. 10.
    Gerstein, M. B., et al. (2012). Architecture of the human regulatory network derived from ENCODE data. Nature, 489, 91–100. Sakabe, N. U., & Nobrega, M. A. (2013). Beyond the ENCODE project. Philosophical Transactions of the Royal Society B, 368, 20130022.Google Scholar
  11. 11.
    Mayran, A., & Drouin, J. (2018). Pioneer transcription factors shape the epigenetic landscape. The Journal of Biological Chemistry, 293, 13795–13804.  https://doi.org/10.1074/jbc.r117.001232.CrossRefGoogle Scholar
  12. 12.
    Frith, M., Pheasant, M., & Mattick J. S. (2005). The amazing complexity of the human transcriptome. European Journal of Human Genetics, 13, 894–897.Google Scholar
  13. 13.
    Prigogine, I. (1980). From being to becoming. San Francisco.Google Scholar
  14. 14.
    Maynard Smith, J. (2000). The concept of information in Biology. Philosophy of Science, 67, 177–194.MathSciNetCrossRefGoogle Scholar
  15. 15.
    Carsetti, A. (2000). Randomness, information and meaningful complexity: Some remarks about the emergence of biological structures. La Nuova Critica, 36, 47–109; Carsetti, A. (2013). Epistemic complexity and knowledge construction. New York: Springer; Carsetti, A. (1987). Teoria algoritmica della informazione e sistemi biologici. La Nuova Critica, 3–4, 37–66.Google Scholar
  16. 16.
    von Foerster, H. (1981). Objects: Tokens for (eigen-) behaviors. Observing systems, the systems, inquiry series. Salinas, CA: Intersystems Publications, [p. 279].Google Scholar

Copyright information

© Springer Nature Switzerland AG 2020

Authors and Affiliations

  1. 1.La Nuova CriticaV. Lariana 7, RomeItaly

Personalised recommendations