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Malignant Transformation of Oral Potentially Malignant Disorders

  • Anura AriyawardanaEmail author
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Part of the Textbooks in Contemporary Dentistry book series (TECD)

Abstract

Prior to noticing any signs and symptoms of an oral squamous cell carcinoma, certain changes may be visible on the oral mucosa that are grouped under the term oral potentially malignant disorders. This concept is based on follow-up studies that have described the natural history of the disease. We present here the evidence that indicates the potentially malignant nature of these disorders.

References

  1. 1.
    Warnakulasuriya S, Johnson NW, van der Waal I. Nomenclature and classification of potentially malignant disorders of the oral mucosa. J Oral Pathol Med. 2007;36(10):575–80.CrossRefGoogle Scholar
  2. 2.
    Markopoulos AK. Current aspects on oral squamous cell carcinoma. Open Dent J. 2012;6:126–30.PubMedPubMedCentralCrossRefGoogle Scholar
  3. 3.
    Reichart PA, PhilipsenH P. Oral erythroplakia--a review. Oral Oncol. 2005;41(6):551–61.PubMedCrossRefPubMedCentralGoogle Scholar
  4. 4.
    Arakeri G, Patil SG, Aljabab AS, et al. Oral submucous fibrosis: an update on pathophysiology of malignant transformation. J Oral Pathol Med. 2017;46(6):413–7.PubMedCrossRefPubMedCentralGoogle Scholar
  5. 5.
    Yang PY, Chen YT, Wang YH, Su NY, Yu HC, Chang YC. Malignant transformation of oral submucous fibrosis in Taiwan: a nationwide population-based retrospective cohort study. J Oral Pathol Med. 2017;46(10):1040–5.PubMedPubMedCentralGoogle Scholar
  6. 6.
    Warnakulasuriya S, Ariyawardana A. Malignant transformation of oral leukoplakia: a systematic review of observational studies. J Oral Pathol Med. 2016;45(3):155–66.CrossRefGoogle Scholar
  7. 7.
    Mehanna HM, Rattay T, Smith J. McConkey. Treatment and follow-up of oral dysplasiada systematic review and meta-analysis. Head Neck. 2009;31:1600–9.PubMedCrossRefPubMedCentralGoogle Scholar
  8. 8.
    Ariyawardana A, Sitheeque MA, Ranasinghe AW, et al. Prevalence of oral cancer and pre-cancer and associated risk factors among tea estate workers in the central Sri Lanka. J Oral Pathol Med. 2007;36(10):581–7.PubMedCrossRefPubMedCentralGoogle Scholar
  9. 9.
    Amarasinghe HK, Usgodaarachchi US, Johnson NW, Lalloo R, Warnakulasuriya S. Betel-quid chewing with or without tobacco is a major risk factor for oral potentially malignant disorders in Sri Lanka: a case-control study. Oral Oncol. 2010;46(4):297–301.PubMedCrossRefPubMedCentralGoogle Scholar
  10. 10.
    Petti S. Pooled estimate of world leukoplakia prevalence: a systematic review. Oral Oncol. 2003;39(8):770–80.CrossRefGoogle Scholar
  11. 11.
    World Health Organization. Definition of leukoplakia and related lesions: an aid to studies on oral precancer. Oral Surg Oral Med Oral Pathol. 1978;46(4):518–36.CrossRefGoogle Scholar
  12. 12.
    Axell T, Holmstrup P, Kramer IRH, Pindborg JJ, Shear M. International seminar on oral leukoplakia and associated lesions related to tobacco habits. Community Dent Oral Epidemiol. 1984;12:145–54.CrossRefGoogle Scholar
  13. 13.
    Axell T, Pindborg JJ, Smith CJ, der van Waal I, and an International Collaborative Group on Oral White Lesions. Oral white lesions with special reference to precancerous and tobacco-related lesions: conclusions of an international symposium held in Uppsala, Sweden, May 18–21, 1994. J Oral Pathol Med. 1996;25:49–54.PubMedCrossRefPubMedCentralGoogle Scholar
  14. 14.
    van der Waal I, Schepman KP, van der Meij EH, Smeele L. Oral leukoplakia: a clinicopathological review. Oral Oncol. 1997;33(5):291–301.PubMedCrossRefPubMedCentralGoogle Scholar
  15. 15.
    Napier SS, Speight PM. Natural history of potentially malignant oral lesions and conditions: an overview of the literature. J Oral Pathol Med. 2008;37(1):1–10.PubMedCrossRefPubMedCentralGoogle Scholar
  16. 16.
    Mehta FS, Pindborg JJ, Gupta PC, Daftary DK. Epidemiologic and histologic study of oral cancer and leukoplakia among 50,915 villagers in India. Cancer. 1969;24(4):832–49.PubMedCrossRefPubMedCentralGoogle Scholar
  17. 17.
    Arduino PG, Bagan J, El-Naggar AK, Carrozzo M. Urban legends series: oral leukoplakia. Oral Dis. 2013;19(7):642–59.PubMedCrossRefPubMedCentralGoogle Scholar
  18. 18.
    van der Waal I. Oral potentially malignant disorders: is malignant transformation predictable and preventable? Medicina Oral Patología Oral y CirugiaBucal. 2014;19:e386–90.CrossRefGoogle Scholar
  19. 19.
    Lee JJ, Hong WK, Hotelman WN, Mao L, et al. Predicting cancer development in oral leukoplakia: ten years of translation research. Clin Cancer Res. 2000;7:1702–10.Google Scholar
  20. 20.
    Einhorn J, Wersall J. Incidence of oral carcinoma in patients with leukoplakia of the oral mucosa. Cancer. 1967;20(12):2189–93.PubMedCrossRefPubMedCentralGoogle Scholar
  21. 21.
    Pindborg JJ, Jolst O, Renstrup G, Roed-Petersen B. Studies in oral leukoplakia: a preliminary report on the period pervalence of malignant transformation in leukoplakia based on a follow-up study of 248 patients. J Am Dent Assoc. 1968;76(4):767–71.PubMedCrossRefPubMedCentralGoogle Scholar
  22. 22.
    Roed-Petersen B. Cancer development in oral leukoplakia follow-up of 331 patients. J Dent Res. 1971;50:711–2.Google Scholar
  23. 23.
    Holmstrup P, Vedtofte P, Reibel J, Stoltze K. Long-term treatment outcome of oral premalignant lesions. Oral Oncol. 2006;42(5):461–74.CrossRefGoogle Scholar
  24. 24.
    Gangadharan P, Paymaster JC. Leukoplakia- an epidemiologicstiudy of 1504 cases observed at the Tata Memorial Hospital, Bombay, India. Br J Cancer. 1971;25(4):657–68.PubMedPubMedCentralCrossRefGoogle Scholar
  25. 25.
    Silverman S, Bhargava K, Smith LW, Malaowalla AM. Malignant transformation and natural history of oral leukoplakia in 57,518 industrial workers of Gujarat, India. Cancer. 1976;38(4):1790–5.PubMedCrossRefPubMedCentralGoogle Scholar
  26. 26.
    Gupta PC, Mehta FS, Daftary DK, Pindborg JJ, et al. Incidence rates of oral cancer and natural history of oral precancerous lesions in a 10-year follow-up study of Indian villagers. Community Dent Oral Epidemiol. 1980;8(6):283–333.PubMedCrossRefPubMedCentralGoogle Scholar
  27. 27.
    Saito T, Sugiura C, Hirai A, Notani K, et al. High malignant transformation rate of widespread multiple oral leukoplakias. Oral Dis. 1999;5:15–9.PubMedCrossRefPubMedCentralGoogle Scholar
  28. 28.
    Hsue SS, Wang WC, Chen CH, et al. Malignant transformation in 1458 patients with potentially malignant oral mucosal disorders: a follow-up study based in a Taiwanese hospital. J Oral Pathol Med. 2007;36(1):25–9.PubMedCrossRefPubMedCentralGoogle Scholar
  29. 29.
    Yen AM, Chen S, Chang S, Chen TH. The effect of betel quid and cigarette on multistate progression of oral pre-malignancy. J Oral Pathol Med. 2008;37:417–22.PubMedCrossRefPubMedCentralGoogle Scholar
  30. 30.
    Liu W, Shi L-J, Wu L, et al. Oral cancer development in patients with leukoplakiaClinicopathological factors affecting outcome. PLoS One. 2012;7(4):e34773.  https://doi.org/10.1371/journal.pone.0034773.CrossRefPubMedPubMedCentralGoogle Scholar
  31. 31.
    Silverman S Jr, Gorsky M, Lozada F. Oral leukoplakia and malignant transformation. A follow-up study of 257 patients. Cancer. 1984;53(3):563–8.PubMedCrossRefPubMedCentralGoogle Scholar
  32. 32.
    Napier SS, Cowan CG, Gregg TA, Stevenson M, et al. Potentially malignant oral lesions in Northern Ireland: size (extent) matters. Oral Dis. 2003;9(3):129–37.PubMedCrossRefPubMedCentralGoogle Scholar
  33. 33.
    Warnakulasuriya S, Kovacevic T, Madden P, et al. Factors predicting malignant transformation in oral potentially malignant disorders among patients accrued over a 10- year period in South East England. J Oral Pathol Med. 2011;40:677–83.PubMedCrossRefPubMedCentralGoogle Scholar
  34. 34.
    Kramer IR, El-Labban N, Lee KW. The clinical features and risk of malignant transformation in sublingual keratosis. Br Dent J. 1978;144:1721–80.CrossRefGoogle Scholar
  35. 35.
    Pogrel MA. Sublingual keratosis and malignant transformation. J Oral Pathol Med. 1979;8:176–8.CrossRefGoogle Scholar
  36. 36.
    Roch-Berry CSB. Malignant changes in glossal leukoplakia. Clin Radiol. 1981;32:693–4.PubMedCrossRefPubMedCentralGoogle Scholar
  37. 37.
    Ho MW, Risk JM, Woolgar JA, et al. Clinical determinants of malignant transformation in oral epithelial dysplasia. Oral Oncol. 2012;48:969–76.PubMedCrossRefPubMedCentralGoogle Scholar
  38. 38.
    Bánóczy J. Follow-up studies in oral leukoplakia. J Maxillofac Surg. 1977;5:69–75.PubMedCrossRefPubMedCentralGoogle Scholar
  39. 39.
    Lind PO. Malignant transformation in oral leukoplakia. Scand J Dent Res. 1987;95(6):449–55.PubMedPubMedCentralGoogle Scholar
  40. 40.
    Hogewind WFC, can der Kwast WAM, van der Wall I. Oral leukoplakia, with emphasis on malignant transformation. J Maxillofac Surg. 1989;17:128–33.Google Scholar
  41. 41.
    Schepman KP, van der Meij EH, Smeele LE, van der Wall I. Malignant transformation of oral leukoplakia: a follow-up study of a hospital based population of 166 patients with leukoplakia from the Netherlands. Oral Oncol. 1998;34:270–5.PubMedCrossRefPubMedCentralGoogle Scholar
  42. 42.
    Brouns E, Baart J, Karagozoglu K, et al. Malignant transformation of oral leukoplakia in a well-defined cohort of 144 patients. Oral Dis. 2014;20(3):e19–24.PubMedCrossRefPubMedCentralGoogle Scholar
  43. 43.
    Arduino PG, Surace A, Carbone M, et al. Outcome of oral dysplasia: a retrospective hospital-based study of 207 patients with a long follow-up. J Oral Pathol Med. 2009;38:540–4.PubMedCrossRefPubMedCentralGoogle Scholar
  44. 44.
    Brzak BL, Mravak-Stipeti CM, Canjuga I, et al. The frequency and malignanttransformation rate of oral lichen planus and leukoplakia-A retrospective study. Coll Anthropol. 2012;36:373–7.Google Scholar
  45. 45.
    Lyu MY, Guo YS, Li S, Yang D, Hua H. Hospital-based epidemiological and clinical characterisation of the malignant transformation of oral leukoplakia in a Chinese population. Int Dent J. 2017;67(4):252–9.PubMedCrossRefPubMedCentralGoogle Scholar
  46. 46.
    Castelo-Branco C, Soveral I. The immune system and aging: a review. Gynecol Endocrinol. 2014;30(1):16–22.PubMedCrossRefPubMedCentralGoogle Scholar
  47. 47.
    El Naggar AK, Reichart PA. Proliferative verrucous leukoplakia and precancerous conditions. In: Barnes L, Eveson JW, Reichart P, Sidransky D, editors. Pathology and genetics of head and neck tumours. Lyon: International Agency for Research on Cancer (IARC), IARC Press; 2005.Google Scholar
  48. 48.
    Bagan J, Scully C, Jimenez Y, Martorell M. Proliferative verrucous leukoplakia: a concise update. Oral Dis. 2010;16(4):328–32.PubMedCrossRefPubMedCentralGoogle Scholar
  49. 49.
    Zakrzewska JM, Lopes V, Speight P, Hopper C. Proliferative verrucous leukoplakia: a report of ten cases. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 1996;82(4):396–401.PubMedCrossRefPubMedCentralGoogle Scholar
  50. 50.
    Silverman S Jr, Gorsky M. Proliferative verrucous leukoplakia: a follow-up study of 54 cases. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 1997;84(2):154–7.PubMedCrossRefPubMedCentralGoogle Scholar
  51. 51.
    Bagan JV, Jimenez-Soriano Y, Diaz-Fernandez JM, et al. Malignant transformation of proliferative verrucous leukoplakia to oral squamous cell carcinoma: a series of 55 cases. Oral Oncol. 2011;47(8):732–5.PubMedCrossRefPubMedCentralGoogle Scholar
  52. 52.
    Capellaa DL, Goncalves JM, Abrantes AAA, Grando LJ, Daniel FI. Proliferative verrucous leukoplakia: diagnosis, management and current advances. Braz J Otorhinolaryngol. 2017;83(5):585–93.CrossRefGoogle Scholar
  53. 53.
    Gale N, Pilch BZ, Sidransky D, Westra WH, Califano J. Epithelial precursor lesions. In: Barnes L, Eveson JW, Reichart P, Sidransky D, editors. World Health Organization classification of tumours. Pathology and genetics of head and neck tumours. Lyon: IARC Press; 2005. p. 140–3.Google Scholar
  54. 54.
    Villa A, Villa C, Abati S. Oral cancer and oral erythroplakia: an update and implication for clinicians. Aust Dent J. 2011;56(3):253–6.PubMedCrossRefPubMedCentralGoogle Scholar
  55. 55.
    Arakeri G, Brennan PA. Oral submucous fibrosis: an overview of the aetiology, pathogenesis, classification, and principles of management. Br J Oral Maxillofac Surg. 2013;51(7):587–93.PubMedCrossRefPubMedCentralGoogle Scholar
  56. 56.
    Tilakaratne WM, EkanayakaR P, Warnakulasuriya S. Oral submucous fibrosis: a historical perspective and a review on etiology and pathogenesis. Oral Surg Oral Med Oral Pathol Oral Radiol. 2016;122(2):178–91.PubMedCrossRefPubMedCentralGoogle Scholar
  57. 57.
    Aziz SR. Oral submucous fibrosis: case report and review of diagnosis and treatment. J Oral Maxillofac Surg. 2008;66(11):2386–9.PubMedCrossRefPubMedCentralGoogle Scholar
  58. 58.
    Sukumar S, ColemanH G, Cox SC. Areca nut chewing in an expatriate population in Sydney: report of two cases. Aust Dent J. 2012;57(3):373–8.PubMedCrossRefGoogle Scholar
  59. 59.
    Cox SC, WalkerD M. Oral submucous fibrosis. A review. Aust Dent J. 1996;41(5):294–9.PubMedCrossRefGoogle Scholar
  60. 60.
    Yang S-F, Wang Y-H, Su N-Y, Yu H-C, Yi WC, Yu C-H, Chang Y-C. Changes in prevalence of precancerous oral submucous fibrosis from 1996 to 2013 in Taiwan: a nationwide population-based retrospective study. J Formos Med Assoc. 2017;  https://doi.org/10.1016/j.jfma.2017.01.012.PubMedCrossRefPubMedCentralGoogle Scholar
  61. 61.
    Paymaster JC. Cancer of the buccal mucosa; a clinical study of 650 cases in Indian patients. Cancer. 1956;9:431–5.PubMedCrossRefPubMedCentralGoogle Scholar
  62. 62.
    International Agency for Research on Cancer WHO. IARC monographs on the evaluation of the carcinogenic risk of chemicals to humans. Betel-quid and areca-nut chewing and somr areca-nut derived nitrosamines, vol. 85. Lyon: IARC; 2004.Google Scholar
  63. 63.
    Ariyawardana A, Athukorala AD, Arulanandam A. Effect of betel chewing, tobacco smoking and alcohol consumption on oral submucous fibrosis: a case-control study in Sri Lanka. J Oral Pathol Med. 2006;35(4):197–201.PubMedCrossRefPubMedCentralGoogle Scholar
  64. 64.
    Ho PS, Yang YH, Shieh TY, et al. Consumption of areca quid, cigarettes, and alcohol related to the comorbidity of oral submucous fibrosis and oral cancer. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2007;104(5):647–52.PubMedCrossRefPubMedCentralGoogle Scholar
  65. 65.
    Pindborg JJ, Murti PR, Bhonsle RB, Gupta PC, Daftary DK, Mehta FS. Oral submucous fibrosis as a precancerous condition. Scand J Dent Res. 1984;92(3):224–9.PubMedPubMedCentralGoogle Scholar
  66. 66.
    Murti PR, Bhonsle RB, Pindborg JJ, Daftary DK, Gupta PC, Mehta FS. Malignant transformation rate in oral submucous fibrosis over a 17-year period. Community Dent Oral Epidemiol. 1985;13(6):340–1.PubMedCrossRefPubMedCentralGoogle Scholar
  67. 67.
    Hazarey VK, Erlewad DM, Mundhe KA, Ughade SN. Oral submucous fibrosis: study of 1000 cases from central India. J Oral Pathol Med. 2007;36(1):12–7.PubMedCrossRefPubMedCentralGoogle Scholar
  68. 68.
    Tang JG, Jian XF, Gao ML, Ling TY, Zhang KH. Epidemiological survey of oral submucous fibrosis in Xiangtan City, Hunan Province, China. Community Dent Oral Epidemiol. 1997;25(2):177–80.PubMedCrossRefPubMedCentralGoogle Scholar
  69. 69.
    Wang YY, Tail YH, Wang WC. Malignant transformation in 5071 southern Taiwanese patients with potentially malignant oral mucosal disorders. BMC Oral Health. 2014;14:99.PubMedPubMedCentralCrossRefGoogle Scholar
  70. 70.
    LianIe B, Tseng YT, Su CC, Tsai KY. Progression of precancerous lesions to oral cancer: results based on the Taiwan National Health Insurance Database. Oral Oncol. 2013;49(5):427–30.CrossRefGoogle Scholar
  71. 71.
    Sinor PN, Gupta PC, Murti PR. A case-control study of oral submucous fibrosis with special reference to the etiologic role of areca nut. J Oral Pathol Med. 1990;19(2):94–8.PubMedCrossRefPubMedCentralGoogle Scholar
  72. 72.
    Shah N, Sharma PP. Role of chewing and smoking habits in the etiology of oral submucous fibrosis (OSF): a case-control study. J Oral Pathol Med. 1998;27(10):475–9.PubMedCrossRefPubMedCentralGoogle Scholar
  73. 73.
    McCartan BE, Healy CM. The reported prevalence of oral lichen planus: a review and critique. J Oral Pathol Med. 2008;37(8):447–53.PubMedCrossRefPubMedCentralGoogle Scholar
  74. 74.
    Gonzalez-Moles MA, Scully C, Gil-Montoya JA. Oral lichen planus: controversies surrounding malignant transformation. Oral Dis. 2008;14(3):229–43.PubMedCrossRefPubMedCentralGoogle Scholar
  75. 75.
    Roopashree MR, Gondhalekar RV, Shashikanth MC, George J, Thippeswamy SH, Shukla A. Pathogenesis of oral lichen planus--a review. J Oral Pathol Med. 2010;39(10):729–34.PubMedCrossRefPubMedCentralGoogle Scholar
  76. 76.
    Otero-Rey EM, Suarez-Alen F, Penamaria-Mallon M, Lopez-Lopez J, Blanco-Carrion A. Malignant transformation of oral lichen planus by a chronic inflammatory process. Use of topical corticosteroids to prevent this progression? Acta Odontol Scand. 2014;72(8):570–7.PubMedCrossRefPubMedCentralGoogle Scholar
  77. 77.
    Krutchkoff DJ, Cutler L, Laskowski S. Oral lichen planus: the evidence regarding potential malignant transformation. J Oral Pathol. 1978;7(1):1–7.PubMedCrossRefPubMedCentralGoogle Scholar
  78. 78.
    van der Meij EH, Schepman KP, Smeele LE, van der Wal JE, Bezemer PD, van der Waal I. A review of the recent literature regarding malignant transformation of oral lichen planus. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 1999;88(3):307–10.PubMedCrossRefPubMedCentralGoogle Scholar
  79. 79.
    Fitzpatrick SG, HirschS A, GordonS C. The malignant transformation of oral lichen planus and oral lichenoid lesions: a systematic review. J Am Dent Assoc. 2014;145(1):45–56.PubMedCrossRefPubMedCentralGoogle Scholar
  80. 80.
    van der Meij EH, Mast H, van der Waal I. The possible premalignant character of oral lichen planus and oral lichenoid lesions: a prospective five-year follow-up study of 192 patients. Oral Oncol. 2007;43(8):742–8.PubMedCrossRefPubMedCentralGoogle Scholar
  81. 81.
    van der Meij EH, van der Waal I. Lack of clinicopathologic correlation in the diagnosis of oral lichen planus based on the presently available diagnostic criteria and suggestions for modifications. J Oral Pathol Med. 2003;32(9):507–12.PubMedCrossRefPubMedCentralGoogle Scholar
  82. 82.
    Aghbari SMH, Abushouk AI, Attia A, et al. Malignant transformation of oral lichen planus and oral lichenoid lesions: a meta-analysis of 20095 patient data. Oral Oncol. 2017;68:92–102.PubMedCrossRefPubMedCentralGoogle Scholar
  83. 83.
    Mignogna MD, Fedele S, Lo Russo L, Mignogna C, de Rosa G, Porter SR. Field cancerization in oral lichen planus. Eur J Surg Oncol. 2007;33(3):383–9.PubMedCrossRefPubMedCentralGoogle Scholar
  84. 84.
    Carrozzo M, Quadri R, Latorre P, et al. Molecular evidence that the hepatitis C virus replicates in the oral mucosa. J Hepatol. 2002;37(3):364–9.PubMedCrossRefPubMedCentralGoogle Scholar
  85. 85.
    Nagao Y, Sata M, Tanikawa K, Itoh K, Kameyama T. High prevalence of hepatitis C virus antibody and RNA in patients with oral cancer. J Oral Pathol Med. 1995;24(8):354–60.PubMedCrossRefPubMedCentralGoogle Scholar
  86. 86.
    Cavalcante AS, AnbinderA L, CarvalhoY R. Actinic cheilitis: clinical and histological features. J Oral Maxillofac Surg. 2008;66(3):498–503.PubMedCrossRefPubMedCentralGoogle Scholar
  87. 87.
    Markopoulos A, Albanidou-Farmaki E, Kayavis I. Actinic cheilitis: clinical and pathologic characteristics in 65 cases. Oral Dis. 2004;10(4):212–6.PubMedCrossRefPubMedCentralGoogle Scholar
  88. 88.
    de Santana Sarmento DJ, da Costa Miguel MC, Queiroz LM, Godoy GP, da Silveira EJ. Actinic cheilitis: clinicopathologic profile and association with degree of dysplasia. Int J Dermatol. 2014;53(4):466–72.PubMedCrossRefPubMedCentralGoogle Scholar
  89. 89.
    Dancyger A, Heard V, Huang B, Suley C, Tang D, Ariyawardana A. Malignant transformation of actinic cheilitis: a systematic review of observational studies. J Clin Invest Dent. 2018. In pressGoogle Scholar
  90. 90.
    de Oliveira Ribeiro A, da SilvaL C, Martins-Filho PR. Prevalence of and risk factors for actinic cheilitis in Brazilian fishermen and women. Int J Dermatol. 2014;53(11):1370–6.PubMedCrossRefPubMedCentralGoogle Scholar
  91. 91.
    Wood NH, Khammissa R, Meyerov R, Lemmer J, Feller L. Actinic Cheilitis: a case report and a review of the literature. Eur J Dent. 2011;5(1):101–6.PubMedPubMedCentralGoogle Scholar
  92. 92.
    Ortiz GM, PierceA M, Wilson DF. Palatal changes associated with reverse smoking in Filipino women. Oral Dis. 1996;2(3):232–7.PubMedCrossRefPubMedCentralGoogle Scholar
  93. 93.
    Pindborg JJ, Mehta FS, Gupta PC, Daftary DK, Smith CJ. Reverse smoking in Andhra Pradesh, India: a study of palatal lesions among 10,169 villagers. Br J Cancer. 1971;25(1):10–20.PubMedPubMedCentralCrossRefGoogle Scholar
  94. 94.
    Bharath TS, Kumar NG, Nagaraja A, Saraswathi TR, Babu GS, Raju PR. Palatal changes of reverse smokers in a rural coastal Andhra population with review of literature. J Oral Maxillofac Pathol. 2015;19(2):182–7.PubMedPubMedCentralCrossRefGoogle Scholar
  95. 95.
    Neville BW, Damm DD, Allen CM, Bouquot JE. Oral and maxillofacial pathology. 4th ed: Elsevier; Saunders; 2016.Google Scholar
  96. 96.
    van der Eb MM, Leyten EM, Gavarasana S, Vandenbroucke JP, Kahn PM, Cleton FJ. Reverse smoking as a risk factor for palatal cancer: a cross-sectional study in rural Andhra Pradesh, India. Int J Cancer. 1993;54(5):754–8.PubMedCrossRefPubMedCentralGoogle Scholar
  97. 97.
    Morrow RC, Suarez G. Mucosal changes and cancer in intra-oral smoking. Laryngoscope. 1971;81(7):1020–8.PubMedCrossRefPubMedCentralGoogle Scholar
  98. 98.
    Liu W, Shen ZY, Wang LJ, et al. Malignant potential of oral and labial chronic discoid lupus erythematosus: a clinicopathological study of 87 cases. Histopathology. 2011;59(2):292–8.PubMedCrossRefPubMedCentralGoogle Scholar
  99. 99.
    Handlers JP, Abrams AM, Aberle AM, Auyong T, Melrose RJ. Squamous cell carcinoma of the lip developing in discoid lupus erythematosus. Oral Surg Oral Med Oral Pathol. 1985;60(4):382–6.PubMedCrossRefPubMedCentralGoogle Scholar
  100. 100.
    Schiodt M. Oral discoid lupus erythematosus. III. A histopathologic study of sixty-six patients. Oral Surg Oral Med Oral Pathol. 1984;57(3):281–93.PubMedCrossRefPubMedCentralGoogle Scholar
  101. 101.
    Noto Z, Tomihara K, Furukawa K, Noguchi M. Dyskeratosiscongenita associated with leukoplakia of the tongue. Int J Oral Maxillofac Surg. 2016;45(6):760–3.PubMedCrossRefPubMedCentralGoogle Scholar
  102. 102.
    Handley TP, McCaul JA, Ogden GR. Dyskeratosis congenita. Oral Oncol. 2006;42(4):331–6.PubMedCrossRefPubMedCentralGoogle Scholar
  103. 103.
    Pinna R, Cocco F, Cagetti MG, Conti G, Milia E, Sardella A, Campus G. Genetic and developmental disorders of the oral mucosa: epidemiology; molecular mechanisms; diagnostic criteria, management. Periodontol. 2000;2018. in pressGoogle Scholar
  104. 104.
    Bongiorno M, Rivard S, Hammer D, Kentosh J. Malignant transformation of oral leukoplakia in a patient with dyskeratosis congenita. Oral Surg Oral Med Oral Pathol Oral Radiol. 2017;124(4):e239–42.PubMedCrossRefPubMedCentralGoogle Scholar
  105. 105.
    Alter BP, Giri N, Savage SA, Rosenberg PS. Cancer in dyskeratosis congenita. Blood. 2009;113(26):6549–57.PubMedPubMedCentralCrossRefGoogle Scholar
  106. 106.
    Bandyopadhyay A, Behura SS, Nishat R, Dash KC, Bhuyan L, Ramachandra S. Clinicopathological profile and malignant transformation in oral lichen planus: a retrospective study. J Int Soc Prev Community Dent. 2017;7(3):116–24.PubMedPubMedCentralGoogle Scholar
  107. 107.
    Irani S. Pre-cancerous lesions in the oral and maxillofacial region: a literature review with special focus on etiopathogenesis. Iran J Pathol. 2016;11(4):303–22.PubMedPubMedCentralGoogle Scholar
  108. 108.
    Lauritano D, Arrica M, Lucchese A, et al. Oral lichen planus clinical characteristics in Italian patients: a retrospective analysis. Head Face Med. 2016;12:18.PubMedPubMedCentralCrossRefGoogle Scholar
  109. 109.
    Varghese SS, George GB, Sarojini SB, et al. Epidemiology of oral lichen planus in a cohort of South Indian population: a retrospective study. J Cancer Prev. 2016;21(1):55–9.PubMedPubMedCentralCrossRefGoogle Scholar
  110. 110.
    Richter I, Andabak-Rogulj A, Vučićević-Boras V, Budimir J, Brailo V. Oral lichen planus–retrospective study of 563 Croatian patients. Medicina oral, patologia oral y cirugia Bucal. 2014;19(3):e255.PubMedPubMedCentralGoogle Scholar
  111. 111.
    Radochová V, Dřízhal I, Slezák R. A retrospective study of 171 patients with oral lichen planus in the East Bohemia-Czech Republic–single center experience. J Clin Exp Dent. 2014;6(5):e556.PubMedPubMedCentralCrossRefGoogle Scholar
  112. 112.
    Bardellini E, Amadori F, Flocchini P, Bonadeo S, Majorana A. Clinicopathological features and malignant transformation of oral lichen planus: a 12-years retrospective study. Acta Odontol Scand. 2013;71(3–4):834–40.PubMedCrossRefPubMedCentralGoogle Scholar
  113. 113.
    Gumru B. A retrospective study of 370 patients with oral lichen planus in Turkey. Med Oral Patol Oral Cir Bucal. 2013;18(3):e427–32.PubMedPubMedCentralCrossRefGoogle Scholar
  114. 114.
    Ilana K, Yael V-S, Gavriel G, Shlomo C, Anavi Y. The dynamics of oral lichen planus: a retrospective clinicopathological study. Head Neck Pathol. 2012;6:178–83.CrossRefGoogle Scholar
  115. 115.
    Shen Zheng Yu LW, Zhu Lai Kuan, Feng Jin Qiu, Tang Guo Yao, Zhou ZT. A retrospective clinicopathological study on oral lichen planus and malignant transformation: analysis of 518 cases. Medicina oral, patologia oral y cirugia Bucal. 2012;17:943–7.CrossRefGoogle Scholar
  116. 116.
    Bombeccari GP, Guzzi G, Tettamanti M, et al. Oral lichen planus and malignant transformation: a longitudinal cohort study. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2011;112(3):328–34.PubMedCrossRefPubMedCentralGoogle Scholar
  117. 117.
    Bermejo-Fenoll A, Sánchez-Siles M, López-Jornet P, Camacho-Alonso F, Salazar-Sánchez N. A retrospective clinicopathological study of 550 patients with oral lichen planus in South-Eastern Spain. J Oral Pathol Med. 2010;39(6):491–6.PubMedCrossRefPubMedCentralGoogle Scholar
  118. 118.
    Torrente-Castells Eulàlia FR, Leonardo B-A, Cosme G-E. Clinical features of oral lichen planus. A retrospective study of 65cases. Med Oral Patol Oral Cir Bucal. 2010;15:e685–90.PubMedCrossRefPubMedCentralGoogle Scholar
  119. 119.
    Carbone M, Arduino PG, Carrozzo M, et al. Course of oral lichen planus: a retrospective study of 808 northern Italian patients. Oral Dis. 2009;15(3):235–43.PubMedCrossRefPubMedCentralGoogle Scholar
  120. 120.
    Xue JL, Fan MW, Wang SZ, Chen XM, Li Y, Wang L. A clinical study of 674 patients with oral lichen planus in China. J Oral Pathol Med. 2005;34(8):467–72.PubMedCrossRefPubMedCentralGoogle Scholar
  121. 121.
    van der Meij, Mast EH, van der Waal I. The possible premalignant character of oral lichen planus and oral lichenoid lesions: a prospective study. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2003;96(2):164–71.PubMedCrossRefPubMedCentralGoogle Scholar

Copyright information

© Springer Nature Switzerland AG 2020

Authors and Affiliations

  1. 1.College of Medicine and Dentistry, Cairns Campus, James Cook UniversityCairnsAustralia
  2. 2.Metro South Oral HealthWooloongabbaAustralia

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