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Occupational Risk Factors of Laryngeal Cancer

  • Paolo BoffettaEmail author
  • Francesca Donato
Chapter
  • 38 Downloads

Abstract

Laryngeal cancer affects mainly heavy smokers and excessive drinkers. The evidence for a causal association is strong for asbestos and strong inorganic acid mists. The relative risk of laryngeal cancer among workers exposed to asbestos is in the order of 1.2, with limited evidence of a gradient in risk according to duration or level of exposure. An association between exposure to mists of strong inorganic acids, mainly sulfuric acid, and laryngeal cancer has been reported in both cohort and case–control studies, but the quantification of the excess risk is complicated by heterogeneity in study results. Several other agents have been suggested to increase the risk of laryngeal cancer, including polycyclic aromatic hydrocarbons, wood dust, diesel engine exhaust, and organic solvents, but the evidence is weak and inconsistent. An increased risk has been reported for occupational groups with exposure to known carcinogens (e.g., cooks, waiters, plumbers), and for other groups without clear exposure to known carcinogens (e.g., shoe workers). Residual confounding by tobacco smoking and alcohol drinking, two strong risk factors of the disease, remains a concern in many available studies. In most populations, occupational exposures are likely to play a minor role in laryngeal carcinogenesis.

Keywords

Larynx Laryngeal cancer Epidemiology Occupational exposure Workers 

References

  1. 1.
    Forman D, Bray F, Brewster DH, et al. Cancer incidence in five continents, vol. 10. Lyon: IARC; 2013.Google Scholar
  2. 2.
    Ferlay J, Soerjomataram I, Ervik M, et al. Globocan 2012 v1.0, Cancer incidence and mortality worldwide: IARC CancerBase no. 11. Lyon: International Agency for Research on Cancer; 2013.Google Scholar
  3. 3.
    Olshan FA. Cancer of the larynx. In: Schottenfeld D, Fraumeni JF, editors. Cancer epidemiology and prevention. New York: Oxford University Press; 2006. p. 627–37.CrossRefGoogle Scholar
  4. 4.
    World Cancer Research Fund/American Institute for Cancer Research. Food, nutrition, physical activity, and the prevention of cancer: a global perspective. Washington, DC: AICR; 2006.Google Scholar
  5. 5.
    Li X, Gao L, Li H, et al. Human papillomavirus infection and laryngeal cancer risk: a systematic review and meta-analysis. J Infect Dis. 2013;207:479–88.PubMedCrossRefGoogle Scholar
  6. 6.
    McKay JD, Truong T, Gaborieau V, et al. A genome-wide association study of upper aerodigestive tract cancers conducted within the INHANCE consortium. PLoS Genet. 2011;7:e1001333.PubMedPubMedCentralCrossRefGoogle Scholar
  7. 7.
    De Angelis R, Sant M, Coleman MP, et al. Cancer survival in Europe 1999-2007 by country and age: results of EUROCARE-5-a population-based study. Lancet Oncol. 2014;15:23–34.PubMedCrossRefGoogle Scholar
  8. 8.
    Axelson O, Steenland K. Indirect methods of assessing the effects of tobacco use in occupational studies. Am J Ind Med. 1988;13:105–18.PubMedCrossRefGoogle Scholar
  9. 9.
    Gandini S, Botteri E, Iodice S, et al. Tobacco smoking and cancer: a meta-analysis. Int J Cancer. 2008;122:155–64.PubMedCrossRefGoogle Scholar
  10. 10.
    Roggli VL, Greenberg SD, McLarty JL, et al. Asbestos body content of the larynx in asbestos workers: a study of five cases. Arch Otolaryngol. 1980;106:533–5.PubMedCrossRefGoogle Scholar
  11. 11.
    Kambic V, Radsel Z, Gale N. Alterations in the laryngeal mucosa after exposure to asbestos. Br J Ind Med. 1989;46:717–23.PubMedPubMedCentralGoogle Scholar
  12. 12.
    Hesterberg TW, Miiller WC, McConnell EE, et al. Chronic inhalation toxicity of size-separated glass fibers in Fischer 344 rats. Fundam Appl Toxicol. 1993;20:464–76.PubMedCrossRefGoogle Scholar
  13. 13.
    Hesterberg TW, Miller WC, Mast R, et al. Relationship between lung biopersistence and biological effects of man-made vitreous fibers after chronic inhalation in rats. Environ Health Perspect. 1994;102(Suppl 5):133–7.PubMedPubMedCentralCrossRefGoogle Scholar
  14. 14.
    McConnell EE. Synthetic vitreous fibers—inhalation studies. Regul Toxicol Pharmacol. 1994;20:S22–34.PubMedGoogle Scholar
  15. 15.
    McConnell EE, Kamstrup O, Musselman R, et al. Chronic inhalation study of size-separated rock and slag wool insulation fibers in Fischer 344/N rats. Inhal Toxicol. 1994;6:571–614.CrossRefGoogle Scholar
  16. 16.
    McConnell EE, Axten C, Hesterberg TW, et al. Studies on the inhalation toxicology of two fiberglasses and amosite asbestos in the Syrian golden hamster. Part II. Results of chronic exposure. Inhal Toxicol. 1999;11:785–835.PubMedCrossRefGoogle Scholar
  17. 17.
    Allen EM, Alexander BH, MacLehose RF, et al. Cancer incidence among Minnesota taconite mining industry workers. Ann Epidemiol. 2015;25:811–5.PubMedPubMedCentralCrossRefGoogle Scholar
  18. 18.
    Sathiakumar N, Delzell E, Amoateng-Adjepong Y, et al. Epidemiologic evidence on the relationship between mists containing sulfuric acid and respiratory tract cancer. Crit Rev Toxicol. 1997;27:233–51.PubMedCrossRefGoogle Scholar
  19. 19.
    International Agency for Research on Cancer. Occupational exposures to mists and vapours from strong inorganic acids and other industrial chemicals. IARC Monogr Eval Carcinog Risks Hum. 1992;54:1–310.Google Scholar
  20. 20.
    Berrino F, Richiardi L, Boffetta P, et al. Occupation and larynx and hypopharynx cancer: a job-exposure matrix approach in an international casecontrol study in France, Italy, Spain and Switzerland. Cancer Causes Control. 2003;14:213–23.PubMedCrossRefGoogle Scholar
  21. 21.
    Checkoway H, Boffetta P, Mundt DJ, et al. Critical review and synthesis of the epidemiologic evidence on formaldehyde exposure and risk of leukemia and other lymphohematopoietic malignancies. Cancer Causes Control. 2012;23:1747–66.PubMedPubMedCentralCrossRefGoogle Scholar
  22. 22.
    Coggon D, Ntani G, Harris CE, et al. Upper airway Cancer, myeloid leukemia, and other cancers in a cohort of British chemical workers exposed to formaldehyde. Am J Epidemiol. 2014;179:1301–11.PubMedPubMedCentralCrossRefGoogle Scholar
  23. 23.
    Hansen J, Olsen JH. Formaldehyde and cancer morbidity among male employees in Denmark. Cancer Causes Control. 1995;6:354–60.PubMedCrossRefGoogle Scholar
  24. 24.
    Hauptmann M, Lubin JH, Stewart PA, et al. Mortality from solid cancers among workers in formaldehyde industries. Am J Epidemiol. 2004;159:1117–30.PubMedCrossRefGoogle Scholar
  25. 25.
    Laforest L, Luce D, Golberg P, et al. Laryngeal and hypopharyngeal cancers and occupational exposure to formaldehyde and various dusts: a case-control study in France. Occup Environ Med. 2000;57:767–73.PubMedPubMedCentralCrossRefGoogle Scholar
  26. 26.
    Pinkerton LE, Hein MJ, Stayner LT. Mortality among a cohort of garment workers exposed to formaldehyde: an update. Occup Environ Med. 2004;61:193–200.PubMedPubMedCentralCrossRefGoogle Scholar
  27. 27.
    Pira E, Romano C, Verga F, La Vecchia C. Mortality from lymphohematopoietic neoplasms and other causes in a cohort of laminated plastic workers exposed to formaldehyde. Cancer Causes Control. 2014;25:1343–9.PubMedCrossRefGoogle Scholar
  28. 28.
    Shangina O, Brennan P, Szeszenia-Dabrowska N, et al. Occupational exposure and laryngeal and hypopharyngeal cancer risk in central and eastern Europe. Am J Epidemiol. 2006;164:367–75.PubMedCrossRefGoogle Scholar
  29. 29.
    Walrath J, Fraumeni J. Cancer and other causes of death among embalmers. Cancer Res. 1984;44:4638–41.PubMedGoogle Scholar
  30. 30.
    Wortley P, Vaughan TL, Davis S, et al. A case-control study of occupational risk factors for laryngeal cancer. Br J Ind Med. 1992;49:837–44.PubMedPubMedCentralGoogle Scholar
  31. 31.
    Boffetta P, Jourenkova N, Gustavsson P. Cancer risk from occupational and environmental exposure to polycyclic aromatic hydrocarbons. Cancer Causes Control. 1997;8:444–72.PubMedCrossRefPubMedCentralGoogle Scholar
  32. 32.
    Bosetti C, Boffetta P, La Vecchia C. Occupational exposures to polycyclic aromatic hydrocarbons, and respiratory and urinary tract cancers: a quantitative review to 2005. Ann Oncol. 2007;18:431–46.PubMedCrossRefPubMedCentralGoogle Scholar
  33. 33.
    Wagner M, Bolm-Audorff U, Hegewald J, et al. Occupational polycyclic aromatic hydrocarbon exposure and risk of larynx cancer: a systematic review and meta-analysis. Occup Environ Med. 2015;72:226–33.PubMedCrossRefGoogle Scholar
  34. 34.
    Brown LM, Mason TJ, Pickle LW, et al. Occupational risk factors for laryngeal cancer on the Texas Gulf Coast. Cancer Res. 1988;48:1960–4.PubMedGoogle Scholar
  35. 35.
    Elci OC, Akpinar-Elci M, Blair A, et al. Risk of laryngeal Cancer by occupational chemical exposure in Turkey. J Occup Environ Med. 2003;45:1100–6.PubMedCrossRefGoogle Scholar
  36. 36.
    Ahrens W, Jockel K, Patzak W, Elsner G. Alcohol, smoking, and occupational factors in cancer of the larynx: a case-control study. Am J Ind Med. 1991;20:477–93.PubMedCrossRefGoogle Scholar
  37. 37.
    Boffetta P, Richiardi L, Berrino F, et al. Occupation and larynx and hypopharynx cancer: an international case-control study in France, Italy, Spain, and Switzerland. Cancer Causes Control. 2003;14:203–12.PubMedCrossRefGoogle Scholar
  38. 38.
    Langevin SM, Mc Clean MD, Michaud DS, et al. Occupational dust exposure and head and neck squamous cell carcinoma risk in a population-based case–control study conducted in the greater Boston area. Cancer Med. 2013;2:978–86.PubMedPubMedCentralCrossRefGoogle Scholar
  39. 39.
    Steenland K, Barry V, Antilla A, et al. A cohort mortality study of lead-exposed workers in the USA, Finland and the UK. Occup Environ Med. 2017;74:785–91.PubMedCrossRefGoogle Scholar
  40. 40.
    Seilkop SK, Lightfoot NE, Berriault CJ, et al. Respiratory cancer mortality and incidence in an updated cohort of Canadian nickel production workers. Arch Environ Occup Health. 2017;72:204–9.PubMedCrossRefGoogle Scholar
  41. 41.
    Barul C, Fayossé A, Carton M, et al. Occupational exposure to chlorinated solvents and risk of head and neck cancer in men: a population-based case-control study in France. Environ Health. 2017;16:77.PubMedPubMedCentralCrossRefGoogle Scholar
  42. 42.
    Scarnato C, Rambaldi R, Mancini G, et al. Mortality study update of workers exposed to vinyl chloride in plants located in Ferrara and Ravenna (Emilia-Romagna, Northern Italy). Epidemiol Prev. 2017;41:271–8.PubMedGoogle Scholar
  43. 43.
    van den Borre L, Deboosere P. Enduring health effects of asbestos use in Belgian industries: a record-linked cohort study of cause-specific mortality (2001–2009). BMJ Open. 2015;5:e007384.PubMedPubMedCentralCrossRefGoogle Scholar
  44. 44.
    De Stefani E, Boffetta P, Oreggia F, et al. Occupation and the risk of laryngeal cancer in Uruguay. Am J Ind Med. 1998;33:537–42.PubMedCrossRefGoogle Scholar
  45. 45.
    Gustavsson P, Jakobsson R, Johansson H, et al. Occupational exposures and squamous cell carcinoma of the oral cavity, pharynx, larynx, and oesophagus: a case-control study in Sweden. Occup Environ Med. 1998;55:393–400.PubMedPubMedCentralCrossRefGoogle Scholar
  46. 46.
    Goldberg P, Leclerc A, Luce D, et al. Laryngeal and hypopharyngeal cancer and occupation: results of a case control-study. Occup Environ Med. 1997;54:477–82.PubMedPubMedCentralCrossRefGoogle Scholar
  47. 47.
    Pollán M, López-Abente G. Wood-related occupations and laryngeal cancer. Cancer Detect Prev. 1995;19:250–7.PubMedGoogle Scholar
  48. 48.
    Elci OC, Dosemeci M, Blair A. Occupation and the risk of laryngeal cancer in Turkey. Scand J Work Environ Health. 2001;27:233–9.PubMedCrossRefGoogle Scholar
  49. 49.
    ReijulA J, Kjaerheim K, Lynge E, et al. Cancer incidence among waiters: 45 years of follow-up in five Nordic countries. Scand J Public Health. 2015;43:204–11.PubMedCrossRefGoogle Scholar
  50. 50.
    Zagraniski RT, Kelsey JL, Walter SD. Occupational risk factors for laryngeal carcinoma: Connecticut, 1975-1980. Am J Epidemiol. 1986;124:67–76.PubMedCrossRefGoogle Scholar
  51. 51.
    Stenehjem JS, Kjærheim K, Rabanal KS, et al. Cancer incidence among 41,000 offshore oil industry workers. Occup Med. 2014;64:539–45.CrossRefGoogle Scholar
  52. 52.
    International Agency for Research on Cancer. Occupational exposures in the rubber-manufacturing industry. IARC Monogr Eval Carcinog Risks Hum. 2012;100F:541–62.Google Scholar
  53. 53.
    Vlaanderen J, Taeger D, Wellman J, et al. Extended cancer mortality follow-up of a German rubber industry cohort. J Occup Environ Med. 2013;55:966–72.PubMedCrossRefGoogle Scholar
  54. 54.
    Boniol M, Koechlin A, Boyle P. Meta-analysis of occupational exposures in the rubber manufacturing industry and risk of cancer. Int J Epidemiol. 2017;46:1940.PubMedCrossRefPubMedCentralGoogle Scholar
  55. 55.
    Richardson DB, Cardis E, Daniels RD, et al. Site-specific solid cancer mortality following exposure to ionizing radiation: a cohort study of workers (INWORKS). Epidemiology. 2018;29(1):31–40.PubMedPubMedCentralCrossRefGoogle Scholar
  56. 56.
    Pukkala E, Martinsen JI, Lynge E, et al. Occupation and cancer—follow-up of 15 million people in five Nordic countries. Acta Oncol. 2009;48(5):646–790.PubMedCrossRefPubMedCentralGoogle Scholar
  57. 57.
    Peto J, Doll R, Hermon C, et al. Relationship of mortality to measures of environmental asbestos pollution in an asbestos textile factory. Ann Occup Hyg. 1985;29:305–55.PubMedGoogle Scholar
  58. 58.
    Gardner MJ, Winter PD, Pannett B, Powell CA. Follow up study of workers manufacturing chrysotile asbestos cement products. Br J Ind Med. 1986;43:726–32.PubMedPubMedCentralGoogle Scholar
  59. 59.
    Hughes JM, Weill H, Hammad YY. Mortality of workers employed in two asbestos cement manufacturing plants. Br J Ind Med. 1987;44:161–74.PubMedPubMedCentralGoogle Scholar
  60. 60.
    Enterline PE, Hartley J, Henderson V. Asbestos and cancer: a cohort followed up to death. Br J Ind Med. 1987;44:396–401.PubMedPubMedCentralGoogle Scholar
  61. 61.
    Armstrong BK, de Klerk NH, Musk AW, Hobbs MS. Mortality in miners and millers of crocidolite in Western Australia. Br J Ind Med. 1988;45:5–13.PubMedPubMedCentralGoogle Scholar
  62. 62.
    Tola S, Kalliomaki PL, Pukkala E, Asp S, Korkala ML. Incidence of cancer among welders, platers, machinists, and pipe fitters in shipyards and machine shops. Br J Ind Med. 1988;45:209–18.PubMedPubMedCentralGoogle Scholar
  63. 63.
    Raffn E, Lynge E, Juel K, Korsgaard B. Incidence of cancer and mortality among employees in the asbestos cement industry in Denmark. Br J Ind Med. 1989;46:90–6.PubMedPubMedCentralGoogle Scholar
  64. 64.
    Finkelstein MM. Mortality rates among employees potentially exposed to chrysotile asbestos at two automotive parts factories. Can Med Assoc J. 1989;141:125–30.Google Scholar
  65. 65.
    Parnes SM. Asbestos and cancer of the larynx: is there a relationship? Laryngoscope. 1990;100:254–61.PubMedCrossRefGoogle Scholar
  66. 66.
    Selikoff IJ, Seidman H. Asbestos-associated deaths among insulation workers in the United States and Canada, 1967-1987. Ann N Y Acad Sci. 1991;643:1–14.PubMedCrossRefGoogle Scholar
  67. 67.
    Botta M, Magnani C, Terracini B, et al. Mortality from respiratory and digestive cancers among asbestos cement workers in Italy. Cancer Detect Prev. 1991;15:445–7.PubMedGoogle Scholar
  68. 68.
    Sluis-Cremer GK, Liddell FD, Logan WP, Bezuidenhout BN. The mortality of amphibole miners in South Africa, 1946-80. Br J Ind Med. 1992;49:566–75.PubMedPubMedCentralGoogle Scholar
  69. 69.
    Giaroli C, Belli S, Bruno C, et al. Mortality study of asbestos cement workers. Int Arch Occup Environ Health. 1994;66:7–11.PubMedCrossRefGoogle Scholar
  70. 70.
    Meurman LO, Pukkala E, Hakama M. Incidence of cancer among anthophyllite asbestos miners in Finland. Occup Environ Med. 1994;51:421–5.PubMedPubMedCentralCrossRefGoogle Scholar
  71. 71.
    Berry G. Mortality and cancer incidence of workers exposed to chrysotile asbestos in the friction-products industry. Ann Occup Hyg. 1994;38:539–46.PubMedGoogle Scholar
  72. 72.
    Dement JM, Brown DP, Okun A. Follow-up study of chrysotile asbestos textile workers: cohort mortality and case-control analyses. Am J Ind Med. 1994;26:431–47.PubMedCrossRefGoogle Scholar
  73. 73.
    Tsai SP, Waddell LC, Gilstrap EL, Ransdell JD, Ross CE. Mortality among maintenance employees potentially exposed to asbestos in a refinery and petrochemical plant. Am J Ind Med. 1996;29:89–98.PubMedCrossRefGoogle Scholar
  74. 74.
    Liddell FD, McDonald AD, McDonald JC. The 1891-1920 birth cohort of Quebec chrysotile miners and millers: development from 1904 and mortality to 1992. Ann Occup Hyg. 1997;41:13–36.PubMedCrossRefGoogle Scholar
  75. 75.
    Levin J, McLarty J, Hurst GA, et al. Tyler asbestos workers: mortality experience in a cohort exposed to amosite. Occup Environ Med. 1998;55:155–60.PubMedPubMedCentralCrossRefGoogle Scholar
  76. 76.
    Germani D, Belli S, Bruno C, et al. Cohort mortality study of women compensated for asbestosis in Italy. Am J Ind Med. 1999;36:129–34.PubMedCrossRefGoogle Scholar
  77. 77.
    Karjalainen A, Pukkala E, Kauppinen T, Partanen T. Incidence of cancer among Finnish patients with asbestos-related pulmonary or pleural fibrosis. Cancer Causes Control. 1999;10:51–7.PubMedCrossRefGoogle Scholar
  78. 78.
    Battista G, Belli S, Comba P, et al. Mortality due to asbestos-related causes among railway carriage construction and repair workers. Occup Med. 1999;49:536–9.CrossRefGoogle Scholar
  79. 79.
    Berry G, Newhouse ML, Wagner JC. Mortality from all cancers of asbestos factory workers in East London 1933-1980. Occup Environ Med. 2000;57:782–5.PubMedPubMedCentralCrossRefGoogle Scholar
  80. 80.
    Puntoni R, Merlo F, Borsa L, et al. A historical cohort mortality study among shipyard workers in Genoa, Italy. Am J Ind Med. 2001;40:363–70.PubMedCrossRefGoogle Scholar
  81. 81.
    Szeszenia-Dabrowska N, Urszula W, Szymczak W, Strzelecka A. Mortality study of workers compensated for asbestosis in Poland, 1970-1997. Int J Occup Med Environ Health. 2002;15:267–78.PubMedGoogle Scholar
  82. 82.
    Sun T, Li L, Shi N, Zhang X. A 40-year cohort study on cancer mortality among female workers with manual spinning of chrysotile asbestos. Wei Sheng Yan Jiu. 2003;32:511–3.PubMedGoogle Scholar
  83. 83.
    Smailyte G, Kurtinaitis J, Andersen A. Cancer mortality and morbidity among Lithuanian asbestos-cement producing workers. Scand J Work Environ Health. 2004;30:64–70.PubMedCrossRefGoogle Scholar
  84. 84.
    Finkelstein MM, Verma DK. A cohort study of mortality among Ontario pipe trades workers. Occup Environ Med. 2004;61:736–42.PubMedPubMedCentralCrossRefGoogle Scholar
  85. 85.
    Wilczynska U, Szymczak W, Szeszenia-Dabrowska N. Mortality from malignant neoplasms among workers of an asbestos processing plant in Poland: results of prolonged observation. Int J Occup Med Environ Health. 2005;18:313–26.PubMedGoogle Scholar
  86. 86.
    Hein MJ, Stayner LT, Lehman E, Dement JM. Follow-up study of chrysotile textile workers: cohort mortality and exposure-response. Occup Environ Med. 2007;64:616–25.PubMedPubMedCentralCrossRefGoogle Scholar
  87. 87.
    Musk AW, de Klerk NH, Reid A, et al. Mortality of former crocidolite (blue asbestos) miners and millers at Wittenoom. Occup Environ Med. 2008;65:541–3.PubMedCrossRefGoogle Scholar
  88. 88.
    Loomis D, Dement JM, Wolf SH, Richardson DB. Lung cancer mortality and fibre exposures among North Carolina asbestos textile workers. Occup Environ Med. 2009;66:535–42.PubMedCrossRefGoogle Scholar
  89. 89.
    Harding AH, Darnton A, Wegerdt J, McElvenny D. Mortality among British asbestos workers undergoing regular medical examinations (1971-2005). Occup Environ Med. 2009;66:487–95.PubMedCrossRefGoogle Scholar
  90. 90.
    Menegozzo S, Comba P, Ferrante D, et al. Mortality study in an asbestos cement factory in Naples, Italy. Ann Ist Super Sanita. 2011;47:296–304.PubMedGoogle Scholar
  91. 91.
    Wang X, Lin S, Yu I, et al. Cause-specific mortality in a Chinese chrysotile textile worker cohort. Cancer Sci. 2013;104:245–9.PubMedCrossRefGoogle Scholar
  92. 92.
    Pira E, Romano C, Violante FS, et al. Updated mortality study of a cohort of asbestos textile workers. Cancer Med. 2016;5:2623–8.PubMedPubMedCentralCrossRefGoogle Scholar
  93. 93.
    Pira E, Romano C, Donato F, Pelucchi C, Vecchia C, Boffetta P. Mortality from cancer and other causes among Italian chrysotile asbestos miners. Occup Environ Med. 2017;74:558–63.PubMedCrossRefGoogle Scholar
  94. 94.
    Ferrante D, Chellini E, Merler E, et al. Italian pool of asbestos workers cohorts: mortality trends of asbestos-related neoplasms after long time since first exposure. Occup Environ Med. 2017;74:887–98.PubMedCrossRefGoogle Scholar
  95. 95.
    Oddone E, Ferrante D, Tunesi S, Magnani C. Mortality in asbestos cement workers in Pavia, Italy: a cohort study. Am J Ind Med. 2017;60:852–66.PubMedCrossRefGoogle Scholar
  96. 96.
    Pira E, Pelucchi C, Buffoni L, et al. Cancer mortality in a cohort of asbestos textile workers. Br J Cancer. 2005;92:580–6.PubMedPubMedCentralCrossRefGoogle Scholar
  97. 97.
    Stell P, McGill T. Asbestos and laryngeal carcinoma. Lancet. 1973;302:416–7.CrossRefGoogle Scholar
  98. 98.
    Shettigara PT, Morgan RW. Asbestos, smoking, and laryngeal carcinoma. Arch Environ Health. 1975;30:517–9.PubMedCrossRefGoogle Scholar
  99. 99.
    Hinds MW, Thomas DB, O’Reilly HP. Asbestos, dental X-rays, tobacco, and alcohol in the epidemiology of laryngeal cancer. Cancer. 1979;44:1114–20.PubMedCrossRefGoogle Scholar
  100. 100.
    Burch JD, Howe GR, Miller AB, Semenciw R. Tobacco, alcohol, asbestos, and nickel in the etiology of cancer of the larynx: a case-control study. J Natl Cancer Inst. 1981;67:1219–24.PubMedGoogle Scholar
  101. 101.
    Olsen J, Sabroe S. Occupational causes of laryngeal cancer. J Epidemiol Community Health. 1984;38:117–21.PubMedPubMedCentralCrossRefGoogle Scholar
  102. 102.
    Muscat J, Wynder E. Tobacco, alcohol, asbestos, and occupational risk factors for laryngeal cancer. Cancer. 1992;69:2244–51.PubMedCrossRefGoogle Scholar
  103. 103.
    Zheng W, Blot WJ, Shu XO, et al. Diet and other risk factors for laryngeal cancer in Shanghai, China. Am J Epidemiol. 1992;136:178–91.PubMedCrossRefGoogle Scholar
  104. 104.
    Marchand JL, Luce D, Leclerc A, et al. Laryngeal and hypopharyngeal cancer and occupational exposure to asbestos and man-made vitreous fibers: results of a case-control study. Am J Ind Med. 2000;37:581–9.PubMedCrossRefGoogle Scholar
  105. 105.
    Elci OC, Akpinar-Elci M, Blair A, et al. Occupational dust exposure and the risk of laryngeal cancer in Turkey. Scand J Work Environ Health. 2002;28:278–84.PubMedCrossRefGoogle Scholar
  106. 106.
    Dietz A, Ramroth H, Urban T, et al. Exposure to cement dust, related occupational groups and laryngeal cancer risk: results of a population based case-control study. Int J Cancer. 2004;108:907–11.PubMedCrossRefGoogle Scholar
  107. 107.
    Menvielle G, Fayossé A, Radoï L, et al. The joint effect of asbestos exposure, tobacco smoking and alcohol drinking on laryngeal cancer risk: evidence from the French population-based case-control study, ICARE. Occup Environ Med. 2016;73:28–33.PubMedCrossRefGoogle Scholar
  108. 108.
    Weil CS, Smyth HF Jr, Nale TW. Quest for a suspected industrial carcinogen. Arch Ind Hyg Occup Med. 1952;5:535–47.Google Scholar
  109. 109.
    Hueper WC. Occupational and environmental cancers of the respiratory system. Berlin/New York: Springer-Verlag; 1966.CrossRefGoogle Scholar
  110. 110.
    Lynch J, Hanis NM, Bird MG, et al. An association of upper respiratory cancer with exposure to diethyl sulfate. J Occup Med. 1979;21:333–41.PubMedGoogle Scholar
  111. 111.
    Ahlborg G Jr, Hogstedt C, Sundell L, Aman CG. Laryngeal cancer and pickling house vapors. Scand J Work Environ Health. 1981;7:239–40.PubMedCrossRefGoogle Scholar
  112. 112.
    Cooper WC, Wong O, Kheifets L. Mortality among employees of lead battery plants and lead-producing plants, 1947–1980. Scand J Work Environ Health. 1985;11:331–45.PubMedCrossRefGoogle Scholar
  113. 113.
    Forastiere F, Valesini S, Salimei E, et al. Respiratory cancer among soap production workers. Scand J Work Environ Health. 1987;13:258–60.PubMedCrossRefGoogle Scholar
  114. 114.
    Block G, Matanoski GM, Seltser R, Mitchell T. Cancer morbidity and mortality in phosphate workers. Cancer Res. 1988;48:7298–303.PubMedGoogle Scholar
  115. 115.
    Steenland K, Beaumont J. Further follow-up and adjustment for smoking in a study of lung cancer and acid mists. Am J Ind Med. 1989;16:347–54.PubMedCrossRefGoogle Scholar
  116. 116.
    Teta MJ, Perlman GD, Ott MG. Mortality study of ethanol and isopropanol production workers at two facilities. Scand J Work Environ Health. 1992;18:90–6.PubMedCrossRefGoogle Scholar
  117. 117.
    Coggon D, Pannett B, Wield G. Upper aerodigestive cancer in battery manufacturers and steel workers exposed to mineral acid mists. Occup Environ Med. 1996;53:445–9.PubMedPubMedCentralCrossRefGoogle Scholar
  118. 118.
    Moulin JJ, Clavel T, Roy D, et al. Risk of lung cancer in workers producing stainless steel and metallic alloys. Int Arch Occup Environ Health. 2000;73:171–80.PubMedCrossRefGoogle Scholar
  119. 119.
    Sorahan T, Esmen NA. Lung cancer mortality in UK nickel-cadmium battery workers, 1947–2000. Occup Environ Med. 2004;61:108–16.PubMedPubMedCentralCrossRefGoogle Scholar
  120. 120.
    Pesatori AC, Consonni D, Rubagotti M, et al. Mortality study in a cohort of workers employed in a plant producing sulphuric acid. Med Lav. 2006;97:735–48.PubMedGoogle Scholar
  121. 121.
    Cookfair D, Wende K, Michalek A, Vena J. A case-control study of laryngeal cancer among workers exposed to sulfuric acid (abstract). Am J Epidemiol. 1985;122:521.Google Scholar
  122. 122.
    Zemla B, Day N, Swiatnicka J, Banasik R. Larynx cancer risk factors. Neoplasma. 1987;34:223–33.PubMedGoogle Scholar
  123. 123.
    Soskolne CL, Jhangri GS, Siemiatycki J, et al. Occupational exposure to sulfuric acid in southern Ontario, Canada, in association with laryngeal cancer. Scand J Work Environ Health. 1992;18:225–32.PubMedCrossRefGoogle Scholar
  124. 124.
    Eisen EA, Tolbert PE, Hallock MF, et al. Mortality studies of machining fluid exposure in the automobile industry. III: a case-control study of larynx cancer. Am J Ind Med. 1994;26:185–202.PubMedCrossRefGoogle Scholar

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© Springer Nature Switzerland AG 2020

Authors and Affiliations

  1. 1.Tisch Cancer Institute, Icahn School of Medicine at Mount SinaiNew YorkUSA
  2. 2.Department of Medical and Surgical SciencesUniversity of BolognaBolognaItaly
  3. 3.Department of Public Health and Pediatric SciencesUniversity of TurinTurinItaly

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