We Begin to Target the Biofilm
Biofilms were unknowingly observed centuries ago. Within the last 70 years, our understanding of biofilms, their morphology, and characteristics has grown. Yet despite an increased understanding, the presence of biofilms and their impact on healthcare are still often overlooked, or misunderstood. Antimicrobial technologies and applications are primarily focused on planktonic bacteria. A targeted approach against the biofilm phenotype is likely to improve infection outcomes wherein biofilms are the source of difficult-to-treat infections.
KeywordsBiofilm history Unexploited opportunity Target Biofilm phenotype Initial inocula Antibiofilm
The opinions and information presented in this chapter are those of the author and do not necessarily reflect the position or policy of the Department of Veterans Affairs or the US Government.
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