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On the Role of Human Umbilical Cord Biomechanics

  • Roberto Brunelli
  • Massimiliano Papi
  • Tiziana Parasassi
  • Marco De Spirito
  • Carmine Pappalettere
  • Luciano LambertiEmail author
Conference paper
Part of the Conference Proceedings of the Society for Experimental Mechanics Series book series (CPSEMS)

Abstract

The most abundant component of the human umbilical cord, the Wharton Jelly (WJ), is a mucous connective tissue consisting in a spongy network of interlacing collagen fibers that forms a continuous soft skeleton encasing umbilical vessels. The link between WJ structure and the pivotal cord function in providing unimpeded blood flow to the developing fetus is still poorly understood. We performed an advanced biomechanical characterization of human umbilical cord samples by planar equibiaxial tension tests. The intrinsic moiré technique was utilized for that purpose. A 3-D finite element analysis was then implemented to simulate the biomechanical response of the cord.

Keywords

Human umbilical cord Intrinsic moiré Mechanical characterization Anisotropy Finite element analysis 

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Copyright information

© Society for Experimental Mechanics, Inc. 2020

Authors and Affiliations

  • Roberto Brunelli
    • 1
  • Massimiliano Papi
    • 2
  • Tiziana Parasassi
    • 3
  • Marco De Spirito
    • 2
  • Carmine Pappalettere
    • 4
  • Luciano Lamberti
    • 4
    Email author
  1. 1.Dipartimento Materno Infantile e Scienze UrologicheUniversità SapienzaRomeItaly
  2. 2.Istituto di FisicaUniversità Cattolica del Sacro CuoreRomeItaly
  3. 3.Istituto di Farmacologia TraslazionaleConsiglio Nazionale delle RicercheRomeItaly
  4. 4.Dipartimento di Meccanica, Matematica e ManagementPolitecnico di BariBariItaly

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