Genetic Markers in Tobacco, Usage for Map Development, Diversity Studies, and Quantitative Trait Loci Analysis

  • Nicolas BakaherEmail author
Part of the Compendium of Plant Genomes book series (CPG)


Tobacco (Nicotiana tabacum L.) is an allotetraploid species in the Solanaceae family and has a complex genome. The first genetic maps of tobacco have been developed using microsatellite markers. Microsatellite markers were also used to create links between genetic maps of various Nicotiana species, providing a platform for synteny analysis. Markers are also an efficient tool to decipher the population genetics of tobacco. The three main tobacco types used in smoking products are flue-cured or Virginia, Burley, and Oriental. The commercial type is translated in genetic divergence resulting from the selection of adapted cultivars associated with agronomical and curing crop practices. Genetic markers are needed for trait discovery via quantitative trait locus mapping. They were used to identify loci involved in leaf surface components (cis-abienol and sucrose esters) and contributing to flavor and aroma characteristics. Another QTL mapping study targeting resistance to soilborne diseases such as black shank and bacterial wilt led to the identification of several loci that provide a better understanding of polygenic disease resistance in tobacco. Today with the availability of the genome sequence, single-nucleotide polymorphisms are being developed in tobacco. They are a fast, reproducible, and cost-efficient screening method for any genetic application from basic research to commercial breeding that may accelerate the pace of discoveries in tobacco.


Tobacco Microsatellite Single-nucleotide polymorphism Quantitative trait locus 


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© Springer Nature Switzerland AG 2020

Authors and Affiliations

  1. 1.PMI R&DPhilip Morris Products S.A.NeuchâtelSwitzerland

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