Depressive and Cognitive Disorders in Climacteric Women

  • Joel RennóJr.
  • Juliana Pires Cavalsan
  • Leiliane Aparecida Diniz Tamashiro


Perimenopause is a period of hormone fluctuations accompanied by physical and affective symptoms of women. Among the most frequent symptoms are hot flashes, depression, and cognitive deficits.

The etiology of these symptoms is complex, but research suggests involvement of altered neurotransmitter systems, increased sensitivity to gonadal hormone fluctuations and psychosocial stress triggers.

This chapter will provide an updated review on diagnosis, prevalence, morbidity, risk factors, and evidence-based treatments that have been effective in treating the symptoms of perimenopause.


Perimenopause Depression Cognition Vasomotor symptoms 


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Copyright information

© Springer Nature Switzerland AG 2020

Authors and Affiliations

  • Joel RennóJr.
    • 1
    • 2
  • Juliana Pires Cavalsan
    • 3
  • Leiliane Aparecida Diniz Tamashiro
    • 3
  1. 1.University of São PauloSão PauloBrazil
  2. 2.Brazilian Association of Psychiatry (ABP)Rio de JaneiroBrazil
  3. 3.Department of Psychiatry, Faculty of Medicine, University of São Paulo and Women’s Mental Health Program of the Institute of Psychiatry of the Hospital das ClinicasFaculty of Medicine, University of São PauloSão PauloBrazil

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