Gastric Bypass pp 411-420 | Cite as

Gastric Bypass in Patients with Metabolic Syndrome

  • Mariano Palermo
  • Maria del Pilar Quevedo
  • Edgardo Serra
  • Marianela Aguirre Ackermann


Metabolic surgery was defined by Varco and Buchwald as “the operative manipulation of a normal organ or organ system to achieve a biological result for a potential health gain.” Type 2 diabetes (T2DM) is one of the largest health emergencies of the twenty-first century. Hyperglycemia defines diabetes, and glycemic control is fundamental to diabetes management. Several trials have provided evidence that appropriate glycemic control could lead to a significant reduction in the risk of long-term diabetic complications. Bariatric surgery was initially developed as a tool for weight reduction in severely obese patients. Gastrointestinal operations have demonstrated, especially those that involve food rerouting through the gastrointestinal tract that are safe and provide better outcomes for weight loss and improvement in glucose metabolism in obese patients with type 2 diabetes (T2DM) in comparison to conventional strategies. Bariatric/metabolic procedures have even shown to cause remission of the disease as well as demonstrated extraordinary benefits on lipids and blood pressure control, suggesting good long-term effects on cardiovascular risk profile and mortality. RYGB technique was the first technique that proved its effectiveness in remission of T2DM in morbidly obese patients. Laparoscopic RYGB is the most accepted and effective procedure; it is also the safest and has the best long-term T2DM remission rates compared with other restrictive techniques. These characteristics postulate laparoscopic RYGB as the gold standard.


Gastric bypass Metabolic syndrome Hyperglycemia Bariatric surgery Metabolic surgery T2DM Remission Laparoscopic surgery Gold standard Follow-up 


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Copyright information

© Springer Nature Switzerland AG 2020

Authors and Affiliations

  • Mariano Palermo
    • 1
  • Maria del Pilar Quevedo
    • 1
  • Edgardo Serra
    • 2
  • Marianela Aguirre Ackermann
    • 1
  1. 1.Division of Bariatric Surgery Centro CIEN – DIAGNOMEDInstitution to the University of Buenos AiresBuenos AiresArgentina
  2. 2.Division of Bariatric Surgery Centro CIEN – DIAGNOMEDAffiliated Institution to the University of Buenos Aires and DAICIM FoundationBuenos AiresArgentina

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