Immune System-Related Diseases and Dental Implant Treatment

  • Xiao-fei Zheng
  • An-chun Mo


Undisturbed and optimal bone healing in the phase of osseointegration is pivotal for dental implant success. Certain medical conditions affect the quality and quantity of bone available, as well as peri-implant bone healing. There are physical proximity and functional relationship between the immune system and bone tissue. Physiological functions of the immune system beneficially regulate the skeleton. However, pathologic conditions of the host immune system also affect bone metabolism, resulting in damage to the bone. In this chapter, immune system-related diseases, including rheumatologic disorders and immunosuppressive conditions, are discussed. For patients with these above diseases or conditions, implant procedures may be risky due to their compromised situation. A brief introduction about the possible effect of the condition on dental implant treatment is presented. The treatment of these patients with dental implants usually requires comprehensive oral and systemic evaluation, careful planning, and good communication between dentist, medical professionals, and patients. The special procedures processed preoperatively, perioperatively, and postoperatively are also listed. This chapter aims to draw dentists’ special attention on these immune-related diseases when considering dental implant treatment. The final goal is to ensure the long-term success of an implant-supported dental rehabilitation in patients with immune system-related diseases.


Rheumatologic disorders Sjögren’s syndrome Immunosuppressive conditions Dental implant 


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Copyright information

© Springer Nature Switzerland AG 2020

Authors and Affiliations

  • Xiao-fei Zheng
    • 1
  • An-chun Mo
    • 2
  1. 1.Department of StomatologyThe First Affiliated Hospital of Zhengzhou UniversityZhengzhouChina
  2. 2.Department of Oral ImplantologyWest China Hospital of Stomatology, Sichuan UniversityChengduChina

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