Advertisement

Simple Bone Cyst

  • Liliana G. Olvi
  • Gustavo M. Lembo
  • Osvaldo Velan
  • Isabela W. da Cunha
  • Eduardo Santini-Araujo
  • Ricardo K. Kalil
Chapter
  • 146 Downloads

Abstract

A simple bone cyst (SBC) is an intramedullary, usually unilocular cystic cavity filled with serous or serosanguineous fluid and lined by a membrane of variable thickness, with greater incidence in males than in females (2 or 3:1). The first two decades of life account for 80% of cases. SBC has a predilection for the proximal humerus (50%), proximal femur (25%), and proximal tibia. Radiologically, it is a well-outlined metaphysiodiaphyseal lucency that is centrally and symmetrically located; it expands, thins, and scallops the cortices. The lesion is not wider than the epiphyseal plate. Histologically, the inner lining of the cyst consists of connective tissue with foci of immature bone trabeculae. The bone marrow spaces are rich in dilated, hyperemic capillaries. Fibrinous deposits are often seen. Treatment is multiple needle aspiration of the fluid of the cyst, and injection of methylprednisolone to promote healing of the lesion.

Keywords

Tumor-like lesion of bone Bone Aneurysmal bone cyst Simple bone cyst Fibrous dysplasia 

Suggested Reading

  1. Ambacher T, Maurer F, Weise K. Spontaneous healing of a juvenile bone cyst of the tibia after pathological fracture. Unfallchirurg. 1999;102:972–4.CrossRefGoogle Scholar
  2. Capanna R, Dal Monte A, Gitelis S, Campanacci M. The natural history of unicameral bone cyst after steroid injection. Clin Orthop Relat Res. 1982;166:204–11.Google Scholar
  3. Fletcher CDM, Bridge JA, Hogendoorn PCW, Mertens F. WHO classification of tumours of soft tissue and bone. 4th ed. Lyon: IARC Press; 2013.Google Scholar
  4. Glowacki M, Ignys-O’Byrne A, Ignys I, Mankowski P, Melzer P. Evaluation of volume and solitary bone cyst remodeling using conventional radiological examination. Skelet Radiol. 2010;39:251–9.CrossRefGoogle Scholar
  5. Glowacki M, Ignys-O’Byrne A, Ignys I, Wroblewska K. Limb shortening in the course of solitary bone cyst treatment – a comparative study. Skelet Radiol. 2011;40:173–9.CrossRefGoogle Scholar
  6. Jaffe HL, Lichtenstein L. Solitary unicameral bone cyst. Arch Surg. 1942;44:1004–25.CrossRefGoogle Scholar
  7. Margau R, Babyn P, Cole W, Smith C, Lee F. MR imaging of simple bone cysts in children: not so simple. Pediatr Radiol. 2000;30:551–7.CrossRefGoogle Scholar
  8. Ottolenghi CE, Schajowicz F, Raffa J. Idiopathic unilocular osseous cyst. Clinical and anatomo-pathological study of 123 cases (Article in French.). Rev Chir Orthop Reparatrice Appar Mot. 1969;55:287–301.PubMedGoogle Scholar
  9. Richkind KE, Mortimer E, Mowery-Rushton P, Fraire A. Translocation (16;20)(p11.2;q13). Sole cytogenetic abnormality in a unicameral bone cyst. Cancer Genet Cytogenet. 2002;137:153–5.CrossRefGoogle Scholar
  10. Sakai Junior N, Pereira MF, Kalil RK. A simple bone cyst of the distal humerus with a t(7;12)(q21;q24.3) in a patient with hypophosphatemic rickets. Cancer Genet. 2012;205:541–3.CrossRefGoogle Scholar
  11. Vasilev V, Andreeff I, Sokolov T, Vidinov N. Clinical-morphological and electron-microscopic studies of the growth plate in solitary bone cysts. Arch Orthop Trauma Surg. 1987;106:232–7.CrossRefGoogle Scholar
  12. Vayego-Lourenco SA. TP53 mutations in a recurrent unicameral bone cyst. Cancer Genet Cytogenet. 2001;124:175–6.CrossRefGoogle Scholar
  13. Vayego SA, De Conti OJ, Varella-Garcia M. Complex cytogenetic rearrangement in a case of unicameral bone cyst. Cancer Genet Cytogenet. 1996;86:46–9.CrossRefGoogle Scholar

Copyright information

© Springer Nature Switzerland AG 2020

Authors and Affiliations

  • Liliana G. Olvi
    • 1
  • Gustavo M. Lembo
    • 2
  • Osvaldo Velan
    • 3
  • Isabela W. da Cunha
    • 4
  • Eduardo Santini-Araujo
    • 5
  • Ricardo K. Kalil
    • 6
  1. 1.Laboratory of Orthopaedic PathologyBuenos AiresArgentina
  2. 2.Department of Anatomic PathologyMedical Sciences FacultySanta FeArgentina
  3. 3.Department of RadiologyHospital ItalianoBuenos AiresArgentina
  4. 4.Department of Anatomic PathologyAC Camargo Cancer CenterSão PauloBrazil
  5. 5.Department of PathologyUniversity of Buenos AiresBuenos AiresArgentina
  6. 6.Department of PathologyA. C. Camargo Cancer CenterSão PauloBrazil

Personalised recommendations