Study of the Microcirculation Through Microscopic Techniques

  • Harry A. J. Struijker-BoudierEmail author


This chapter reviews techniques and methodological aspects of investigating the microcirculation, with a particular emphasis on microscopic techniques. The history of intravital microscopy is briefly introduced, followed by a more detailed description of clinical capillaroscopy. In the last decades several technical innovations advanced the use of hand-held vital microscopes to assess the microcirculation in humans. Non-microscopic methods, such as Laser Doppler flowmetry, tomography and magnetic resonance imaging have been developed to study dynamic, flow-related aspects of the microcirculation.


Microcirculation Capillaroscopy Intravital microscopy Imaging techniques 


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© Springer Nature Switzerland AG 2020

Authors and Affiliations

  1. 1.Department of Pharmacology and Toxicology, Cardiovascular Research Institute MaastrichtMaastricht UniversityMaastrichtThe Netherlands

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