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Comparison of Different Treatment Modalities and Treatment Algorithm for Esophageal Achalasia

  • Nicolás H. Dreifuss
  • Francisco Schlottmann
  • Marco Di Corpo
  • Marco G. Patti
Chapter

Abstract

Available treatments for esophageal achalasia are not curative, but rather aim to eliminate the outflow resistance caused by the non-relaxing lower esophageal sphincter. Nonsurgical modalities include pharmacological therapy, endoscopic botulinum toxin injection, pneumatic dilatation, and per-oral endoscopic myotomy (POEM). Surgical treatments include laparoscopic Heller myotomy and esophagectomy. The aim of this chapter is to review and compare current available treatment modalities for esophageal achalasia and propose an evidence-based treatment algorithm.

Keywords

Achalasia Botulinum toxin injection Pneumatic dilatation POEM Laparoscopic Heller myotomy Esophagectomy 

Notes

Conflicts of Interest

The authors have no conflicts of interest to declare.

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© Springer Nature Switzerland AG 2020

Authors and Affiliations

  • Nicolás H. Dreifuss
    • 1
  • Francisco Schlottmann
    • 2
    • 3
  • Marco Di Corpo
    • 3
    • 4
  • Marco G. Patti
    • 5
    • 6
  1. 1.Department of SurgeryHospital Alemán of Buenos AiresBuenos AiresArgentina
  2. 2.Department of SurgeryHospital Alemán of Buenos Aires, University of Buenos AiresBuenos AiresArgentina
  3. 3.Department of SurgeryUniversity of North CarolinaChapel HillUSA
  4. 4.Department of Medicine and SurgeryUniversity of North CarolinaChapel HillUSA
  5. 5.Department of MedicineCenter for Esophageal Diseases and Swallowing, University of North CarolinaChapel HillUSA
  6. 6.Department of SurgeryCenter for Esophageal Diseases and Swallowing, University of North CarolinaChapel HillUSA

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