• Andrew S. FieldEmail author
  • Luigi Di Bonito
  • Maurizio Pinamonti
  • Pamela Michelow
  • Wendy A. Raymond
  • Torill Sauer
  • Andrew H. S. Lee
  • Mary T. Rickard
  • Lauren Arnold
  • William R. Geddie
  • Fernando Schmitt


This chapter defines a benign FNAB and describes and illustrates the cytological features characteristic of specific benign neoplastic and non-neoplastic breast lesions. For each specific entity the clinical and imaging findings are described, and the key cytological diagnostic criteria are listed. The differential diagnosis and potential pitfalls in interpretation and diagnosis are discussed with emphasis on avoiding a false-positive diagnosis. This is particularly relevant in the diagnosis of fibroadenoma and intraductal papillomas. The category also includes a number of lesions that do not require an epithelial component for definitive diagnosis if the features are concordant with the clinical and radiological findings, including breast abscess, cysts, fat necrosis and granulomatous inflammation. Guidelines for optimal management are provided, tailored to different clinical settings with different resource facilities. Finally, a range of sample reports are provided to facilitate optimal communication with the clinical team.


Benign Breast Fine needle aspiration biopsy cytology Fibroadenoma Intraductal papilloma Fibrocystic change Columnar cell change 


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Copyright information

© Springer Nature Switzerland AG 2020

Authors and Affiliations

  • Andrew S. Field
    • 1
    Email author
  • Luigi Di Bonito
    • 2
  • Maurizio Pinamonti
    • 3
  • Pamela Michelow
    • 4
  • Wendy A. Raymond
    • 5
  • Torill Sauer
    • 6
  • Andrew H. S. Lee
    • 7
  • Mary T. Rickard
    • 8
  • Lauren Arnold
    • 9
  • William R. Geddie
    • 10
  • Fernando Schmitt
    • 11
  1. 1.University of NSW and University of Notre Dame Medical SchoolsSt Vincent’s HospitalSydneyAustralia
  2. 2.Department of PathologyUniversity of TriesteTriesteItaly
  3. 3.Department of PathologyUniversity Hospital of TriesteTriesteItaly
  4. 4.Cytology Unit, Department of Anatomical Pathology, Faculty of Health ScienceUniversity of the Witwatersrand and National Health Laboratory ServiceJohannesburgSouth Africa
  5. 5.Flinders Medical Centre, Flinders University of South Australia and Clinpath LaboratoriesAdelaideAustralia
  6. 6.Akershus University Hospital, Department of PathologyLørenskogNorway
  7. 7.Department of HistopathologyNottingham University HospitalsNottinghamUK
  8. 8.St. George Hospital, BreastScreenSydneyAustralia
  9. 9.Sydney Breast ClinicSydneyAustralia
  10. 10.TorontoCanada
  11. 11.Institute of Molecular Pathology and Immunology of Porto University (IPATIMUP), Medical Faculty of Porto UniversityPortoPortugal

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