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Ethics of Phage Therapy

  • Jan Borysowski
  • Andrzej Górski
Chapter

Abstract

Phage therapy is an experimental method of treatment of antibiotic-resistant bacterial infections. Patients can get access to phages either by enrolling in a clinical trial or during compassionate treatment. Very few clinical trials of phages have been conducted to date. Therefore, so far most patients have got access to phage therapy on a compassionate use basis. The main objective of this chapter is to discuss main issues relevant to ethics of clinical trials and compassionate use of phage therapy. Discussion of compassionate use focuses on whether phage therapy is compliant with the four main principles of medical ethics including non-maleficence, beneficence, justice, and respect for the patient’s autonomy. Moreover, we discuss ethical guidelines which might be helpful for doctors who consider performing phage therapy on a compassionate use basis.

Keywords

Ethics Phage Phage therapy Clinical trial Compassionate use 

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Copyright information

© Springer Nature Switzerland AG 2019

Authors and Affiliations

  • Jan Borysowski
    • 1
  • Andrzej Górski
    • 1
    • 2
  1. 1.Department of Clinical ImmunologyMedical University of WarsawWarsawPoland
  2. 2.Laboratory of Bacteriophages, Ludwik Hirszfeld Institute of Immunology and Experimental TherapyPolish Academy of SciencesWrocławPoland

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