Extracorporeal Membrane Oxygenation (ECMO) and Extracorporeal CO2 Removal (ECCO2R)

  • Eric T. ChangEmail author
  • Lena M. Napolitano


Extracorporeal membrane oxygenation (ECMO) should be considered in cases of severe hypoxemia usually related to severe acute respiratory distress syndrome (ARDS) of many etiologies. ECMO replaces pulmonary function, allows ultra-protective mechanical ventilation settings, and may facilitate lung healing. Extracorporeal CO2 removal (ECCO2R) is an emerging respiratory support strategy that is being studied in patients with chronic obstructive pulmonary disease in an effort to avoid intubation and mechanical ventilation. This chapter reviews how extracorporeal pulmonary support is provided, clinical trial data and outcome prediction.


Extracorporeal membrane oxygenation Acute respiratory distress syndrome Severe hypoxemia Acute respiratory failure Extracorporeal CO2 removal COPD Lung recovery 


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© Springer Nature Switzerland AG 2020

Authors and Affiliations

  1. 1.Department of SurgeryUniversity of MichiganAnn ArborUSA
  2. 2.Department of Surgery, Division of Acute Care Surgery, Trauma and Surgical Critical CareUniversity of Michigan Health SystemAnn ArborUSA

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