Neuromuscular Patients (Amyotrophic Lateral Sclerosis and Other Conditions)

  • Giuseppe FiorentinoEmail author
  • Antonio M. Esquinas
  • Anna Annunziata


Many progressive neuromuscular disorders involve muscles of the respiratory system which are involved in breathing and coughing. Ventilatory assistance becomes an important part of management for patients with advanced neuromuscular disease. The combination of NIV with cough-assist techniques decreases pulmonary morbidity and hospital admissions.

Technological advancements in NIV have led to a significant improvement in ability to treatment these patients.



Amyotrophic lateral sclerosis


Chronic obstructive pulmonary disease


Myotonic dystrophy type 1


Duchenne muscular dystrophy


Non-invasive ventilation


Neuromuscular disorders


Non-invasive positive pressure ventilation


Obstructive sleep apnoea syndrome


Positive end-expiratory pressure


Pressure support ventilation


Quality of life


Sleep disorder breathing


Spinal muscular atrophy


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Copyright information

© Springer Nature Switzerland AG 2020

Authors and Affiliations

  • Giuseppe Fiorentino
    • 1
    Email author
  • Antonio M. Esquinas
    • 2
  • Anna Annunziata
    • 1
  1. 1.UOC di Fisiopatologia e Riabilitazione RespiratoriaMonaldi HospitalNaplesItaly
  2. 2.Intensive Care Unit and Non Invasive Ventilatory UnitHospital Morales MeseguerMurciaSpain

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