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Prognosis Following Acute Exacerbation of COPD Treated with Non-invasive Mechanical Ventilation

  • Roberto Bernabeu-Mora
Chapter

Abstract

Non-invasive mechanical ventilation (NIMV) has been shown to reduce intubation and in-hospital mortality in patients with chronic obstructive pulmonary disease (COPD) exacerbations and acute hypercapnic respiratory failure. This patient group has a poor medium-term prognosis, with high rates of mortality and rehospitalisation in the year following discharge. Specific follow-up programmes are therefore needed for these patients.

Abbreviations

AHRF

Acute hypercapnic respiratory failure

APACHE

Acute physiology and chronic health evaluation

BMI

Body mass index

COPD

Chronic obstructive pulmonary disease

eCOPD

COPD exacerbations

FEV1

Forced expiratory volume in 1 s

MRC

Medical Research Council

NIMV

Non-invasive mechanical ventilation

PaCO2

Partial pressure of carbon dioxide in arterial blood carbon

RCTs

Randomised controlled trials

References

  1. 1.
    Vogelmeier CF, Criner GJ, Martinez FJ, et al. Global strategy for the diagnosis, management, and prevention of chronic obstructive lung disease 2017 report. Am J Respir Crit Care Med. 2017;195:557–82.CrossRefGoogle Scholar
  2. 2.
    Lamprecht B, McBurnie MA, Vollmer WM, et al. BOLD Collaborative Research Group. COPD in never smokers: results from the population-based burden of obstructive lung disease study. Chest. 2011;139:752–63.CrossRefGoogle Scholar
  3. 3.
    Wedzicha JA, Singh R, Mackay AJ. Acute COPD exacerbations. Clin Chest Med. 2014;35:157–63.CrossRefGoogle Scholar
  4. 4.
    Dixit D, Bridgeman MB, Andrews LB, et al. Acute exacerbations of chronic obstructive pulmonary disease: diagnosis, management, and prevention n critically ill patients. Pharmacotherapy. 2015;35:631–48.CrossRefGoogle Scholar
  5. 5.
    Suissa S, Dell’Aniello S, Ernst P. Long-term natural history of chronic obstructive pulmonary disease: severe exacerbations and mortality. Thorax. 2012;67:957–63.CrossRefGoogle Scholar
  6. 6.
    Hoogendoorn M, Hoogenveen RT, Rutten-van Mölken MP, et al. Case fatality of COPD exacerbations: a metaanalysis and statistical modelling approach. Eur Respir J. 2011;37:508–15.CrossRefGoogle Scholar
  7. 7.
    Brochard L, Mancebo J, Wysocki M, et al. Noninvasive ventilation for acute exacerbations of chronic obstructive pulmonary disease. N Engl J Med. 1995;333:817–22.CrossRefGoogle Scholar
  8. 8.
    Lightowler JV, Wedzicha JA, Elliott MW, et al. Non-invasive positive pressure ventilation to treat respiratory failure resulting from exacerbations of chronic obstructive pulmonary disease: Cochrane systematic review and meta-analysis. BMJ. 2003;326:185.CrossRefGoogle Scholar
  9. 9.
    Chandra D, Stamm JA, Taylor B, et al. Outcomes of noninvasive ventilation for acute exacerbations of chronic obstructive pulmonary disease in the United States, 1998-2008. Am J Respir Crit Care Med. 2012;185:152–9.CrossRefGoogle Scholar
  10. 10.
    Bott J, Carroll MP, Conway JH, et al. Randomised controlled trial of nasal ventilation in acute ventilatory failure due to chronic obstructive airways disease. Lancet. 1993;341:1555–7.CrossRefGoogle Scholar
  11. 11.
    Kramer N, Meyer TJ, Meharg J, et al. Randomized, prospective trial of noninvasive positive pressure ventilation in acute respiratory failure. Am J Respir Crit Care Med. 1995;151:1799–806.CrossRefGoogle Scholar
  12. 12.
    Plant PK, Owen JL, Elliott MW. Early use of non-invasive ventilation for acute exacerbations of chronic obstructive pulmonary disease on general respiratory wards: a multicentre randomised controlled trial. Lancet. 2000;355:1931–5.CrossRefGoogle Scholar
  13. 13.
    Plant PK, Owen JL, Parrott S, Elliott MW. Cost effectiveness of ward based noninvasive ventilation for acute exacerbations of chronic obstructive pulmonary disease: economic analysis of randomised controlled trial. BMJ. 2003;326:956.CrossRefGoogle Scholar
  14. 14.
    Confalonieri M, Parigi P, Scartabellati A, et al. Noninvasive mechanical ventilation improves the immediate and long-term outcome of COPD patients with acute respiratory failure. Eur Respir J. 1996;9:422–30.CrossRefGoogle Scholar
  15. 15.
    Bardi G, Pierotello R, Desideri M, et al. Nasal ventilation in COPD exacerbations: early and late results of a prospective, controlled study. Eur Respir J. 2000;15:98–104.CrossRefGoogle Scholar
  16. 16.
    Connors AF, Dawson NV, Thomas C, et al. Outcomes following acute exacerbations of severe chronic obstructive lung disease. Am J Respir Crit Care Med. 1996;154:959–67.CrossRefGoogle Scholar
  17. 17.
    Vitacca M, Clini E, Rubini F, et al. Non-invasive ventilation in severe chronic obstructive lung disease and acute respiratory failure: short- and long-term prognosis. Intensive Care Med. 1996;22:94–100.CrossRefGoogle Scholar
  18. 18.
    Plant PK, Owen JL, Elliott MW. Non-invasive ventilation in acute exacerbations of chronic obstructive pulmonary disease: long term survival and predictors of in-hospital outcome. Thorax. 2001;56:708–12.CrossRefGoogle Scholar
  19. 19.
    Chu CM, Chan VL, Lin AW, et al. Readmission rates and life threatening events in COPD survivors treated with non-invasive ventilation for acute hypercapnic respiratory failure. Thorax. 2004;59:1020–5.CrossRefGoogle Scholar
  20. 20.
    Echave-Sustaeta J, Comeche L, García R, et al. Prognosis following acute exacerbation of COPD treated with non-invasive mechanical ventilation. Arch Bronconeumol. 2010;46:405–10.CrossRefGoogle Scholar
  21. 21.
    Hartl S, Lopez-Campos JL, Pozo-Rodriguez F, et al. Risk of death and readmission of hospital-admitted COPD exacerbations: European COPD Audit. Eur Respir J. 2016;47:14–5.CrossRefGoogle Scholar
  22. 22.
    Chung LP, Winship P, Phung S, et al. Five-year outcome in COPD patients after their first episode of acute exacerbation treated with non-invasive ventilation. Respirology. 2010;15:1084–91.CrossRefGoogle Scholar
  23. 23.
    Elliott MW. Non-invasive ventilation in acute exacerbations of COPD: what happens after hospital discharge? Thorax. 2004;59:1006.CrossRefGoogle Scholar
  24. 24.
    Struik FM, Lacasse Y, Goldstein RS. Nocturnal noninvasive positive pressure ventilation in stable COPD: a systematic review and individual patient data meta-analysis. Respir Med. 2014 Feb;108:329–37.CrossRefGoogle Scholar
  25. 25.
    Duiverman ML, Windisch W, Storre JH. The role of NIV in chronic hypercapnic COPD following an acute exacerbation: the importance of patient selection? Ther Adv Respir Dis. 2016;10:149–57.CrossRefGoogle Scholar
  26. 26.
    Shah NM, D’Cruz RF, Murphy PB. Update: non-invasive ventilation in chronic obstructive pulmonary disease. J Thorac Dis. 2018;10(Suppl 1):S71–9.CrossRefGoogle Scholar
  27. 27.
    Storre JH, Callegari J, Magnet FS. Home noninvasive ventilatory support for patients with chronic obstructive pulmonary disease: patient selection and perspectives. Int J Chron Obstruct Pulmon Dis. 2018;13:753–60.CrossRefGoogle Scholar
  28. 28.
    Murphy PB, Hart N. Home non-invasive ventilation for COPD: how, who and when? Arch Bronconeumol. 2018;54:149–54.CrossRefGoogle Scholar

Copyright information

© Springer Nature Switzerland AG 2020

Authors and Affiliations

  • Roberto Bernabeu-Mora
    • 1
  1. 1.Division of Pneumology, Department of Physical TherapyHospital General Universitario JM Morales Meseguer, University of MurciaMurciaSpain

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