Nocturnal NIV in COPD Patients with Prolonged Hypercapnia After Ventilatory Support for Acute Respiratory Failure

  • Alberto Fernández Carmona
  • María Sevilla Martínez
  • Lorena Olivencia Peña


Home non-invasive ventilation for hypercapnic COPD patients despite being an extended therapy has been studied for years with heterogeneous results and until recently without clear documented benefits.

In this chapter, we will review this controversial topic, distinguishing between exacerbation and stable COPD. In addition, some comments and recommendations about ventilator settings and interfaces will be made.



Six-min-walk distance test


Body mass index


Chronic obstructive pulmonary disease


Expired positive airway pressure


High-intensity non-invasive ventilation


Hypercapnic respiratory failure


Positive inspiratory airway pressure


Long-term non-invasive positive pressure ventilation


Long-term supplementary oxygen treatment


Non-invasive positive pressure ventilation


Obstructive sleep apnea


Quality of life


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Copyright information

© Springer Nature Switzerland AG 2020

Authors and Affiliations

  • Alberto Fernández Carmona
    • 1
  • María Sevilla Martínez
    • 1
  • Lorena Olivencia Peña
    • 1
  1. 1.Intensive Care UnitHospital Universitario Virgen de las NievesGranadaSpain

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