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Pruritic Blisters

  • Anupam Das
  • Piyush Kumar
Chapter

Abstract

  • Chronic bullous disease of childhood (CBDC) and linear IgA disease are similar to one another in histology

  • CBDC begins in childhood and is also called the childhood linear IgA disease

  • Cutaneous lesions in CBDC usually heal without scarring

  • CBCD may show spontaneous remission and mean duration of disease in childhood is about 3.9 years

  • Mild cases and oral lesions respond well to topical corticosteroids while severe cases respond to dapsone or sulfapyridine

Keywords

Chronic bullous disease of childhood Linear IgA disease Corticosteroids Dapsone Sulfapyridine 

References

  1. 1.
    Zone JJ, Taylor TB, Meyer LJ, Petersen MJ. The 97 kDa linear IgA bullous disease antigen is identical to a portion of the extracellular domain of the 180 kDa bullous pemphigoid antigen, BPAg2. J Invest Dermatol. 1998;110(3):207–10.CrossRefGoogle Scholar
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    Chanal J, Ingen-Housz-Oro S, Ortonne N, Duong TA, Thomas M, Valeyrie-Allanore L, Lebrun-Vignes B, Andre C, Roujeau JC, Chosidow O, Wolkenstein P. Linear IgA bullous dermatosis: comparison between the drug-induced and spontaneous forms. Br J Dermatol. 2013;169(5):1041–8.CrossRefGoogle Scholar
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    Jablonska S, Chorzelski TP, Rosinska D, Maciejowska E. Linear IgA bullous dermatosis of childhood (chronic bullous dermatosis of childhood). Clin Dermatol. 1991;9(3):393–401.CrossRefGoogle Scholar
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    Verma R, Vasudevan B, Pragasam V, Dabbas D. Linear IgA disease in an adult with unusual clinical features. Indian Dermatol Online J. 2013;4(2):115–8.CrossRefGoogle Scholar
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    Norris IN, Haeberle MT, Callen JP, Malone JC. Generalized linear IgA dermatosis with palmar involvement. Dermatol Online J. 2015;21:9.Google Scholar

Copyright information

© Springer Nature Switzerland AG 2020

Authors and Affiliations

  • Anupam Das
    • 1
  • Piyush Kumar
    • 2
  1. 1.Department of DermatologyKPC Medical CollegeKolkataIndia
  2. 2.Department of DermatologyKatihar Medical CollegeKatiharIndia

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