Itchy Blisters

  • Yan Ling Kong
  • Emily Yiping Gan


  • Linear IgA bullous dermatosis (LABD) is an autoimmune subepidermal blistering disorder that presents with annular or polycyclic erythematous plaques associated with tense vesicles or bullae

  • A detailed drug history is mandatory, as LABD may be precipitated by drug intake, of which the strongest association is seen with vancomycin

  • LABD may also be associated with inflammatory bowel disease, in particular ulcerative colitis

  • Patients with LABD respond dramatically to dapsone with improvement often noted within a few days of its initiation


Linear IgA bullous dermatosis Dapsone Subepidermal blister 


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Copyright information

© Springer Nature Switzerland AG 2020

Authors and Affiliations

  • Yan Ling Kong
    • 1
  • Emily Yiping Gan
    • 2
  1. 1.National Skin CentreSingaporeSingapore
  2. 2.Dermatology ServiceKK Women’s and Children’s HospitalSingaporeSingapore

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