Blisters on Back and Upper Extremities

  • Gulsen Akoglu


  • Pemphigus vulgaris is the most common type of pemphigus with mucocutaneous and mucosal variants

  • Pemphigus foliaceus presents with superficial flaccid blisters and scales with anti desmoglein 1 antibody

  • Pemphigus vegetans presents with vegetative and papillomatous lesions and pemphigus herpetiformis with grouped and herpetiform small blisters, without papillary dermal antidesmogelin 1 antibody deposits

  • Paraneoplastic pemphigus is associated with underlying malignancy and more severe painful oral lesions

  • Drug-induced types of pemphigus may be triggered by exposure to thiol drugs, such a D-penicillamine and captopril, phenol drugs, or non-thiol non-phenol drugs such as peniciline and cephalosporines


Pemphigus vulgaris Pemphigus foliaceus Pemphigus vegetans d-penicillamine 


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© Springer Nature Switzerland AG 2020

Authors and Affiliations

  • Gulsen Akoglu
    • 1
  1. 1.Gulhane Training and Research Hospital, Dermatology and Venereology ClinicUniversity of Health SciencesAnkaraTurkey

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