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Diarrhea Post-HSCT

  • Beatriz Morillo-Gutierrez
  • Mary SlatterEmail author
Chapter

Abstract

  • Acute graft-versus host disease (GVHD) is one of most frequent complications of hematopoietic stem cell transplantation

  • Acute GVHD is still a cause of significant morbidity and mortality and effort needs to be made in achieving an accurate diagnosis to guide effective management

  • The diagnosis of acute GVHD is mostly clinical

  • The backbone of treatment is induction of immunosuppression depending on the staging of GVHD

  • Prevention of GVHD is of prime importance with the use of good donor matching or specific graft manipulations and adequate pretransplant conditioning

Keywords

Hematopoietic stem cell transplantation Graft-versus host disease Extracorporeal photopheresis 

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Copyright information

© Springer Nature Switzerland AG 2020

Authors and Affiliations

  1. 1.Translational Paediatrics and Infectious Diseases UnitSantiago de Compostela University HospitalSantiago de CompostelaSpain
  2. 2.Department of Paediatric ImmunologyGreat North Children’s Hospital, Royal Victoria InfirmaryNewcastle upon TyneUK
  3. 3.Institute of Cellular MedicineNewcastle UniversityNewcastle upon TyneUK

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