Asthenia and Fatigue

  • Dominique M. A. BullensEmail author
  • Isabelle Meyts


  • The chance to develop celiac disease is five-folds higher in children with severe food allergy than in general population

  • Concomitant autoimmunity and severe IgE-mediated allergy are not uncommon and should alert the physician to exclude more complex diagnoses such as immune dysregulation, polyendocrinopathy, enteropathy-X-linked (IPEX) syndrome, auto immune polyendocrinopathy candidiasis ectodermal dystrophy (APECED) or even celiac disease

  • Asthenia in a well-nourished allergic child should be taken seriously and deserves a thorough workup


Immune dysregulation Polyendocrinopathy enteropathy-X-linked Celiac disease Asthenia 


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Copyright information

© Springer Nature Switzerland AG 2020

Authors and Affiliations

  1. 1.Allergy and Clinical Immunology Research Group, KU LeuvenLeuvenBelgium
  2. 2.Inborn Errors of Immunity, KU LeuvenLeuvenBelgium

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