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Positive HIV and Violet Macular Rash

  • Tangie Ngek Larry
  • Derrick Tembi Efie
Chapter

Abstract

  • Kaposi sarcoma is an AIDS defining, benign tumor of poorly differentiated cell of endothelial origin

  • Kaposi sarcoma is the most common malignancy in patients with HIV

  • Kaposi sarcoma typically appears in skin or oropharynx with persistent initially flat, patches of redish-purpulish color that involute to nodules

  • HHV8 is present in almost all of Kaposi sarcoma lesions

  • Highly active antiretroviral therapy limits or resolves Kaposi sarcoma

Keywords

Kaposi sarcoma AIDS HHV8 

References

  1. 1.
    Stanescu L, Foarfa C, Georgescu AC, Georgescu I. Kaposi’s sarcoma associated with AIDS. Roman J Morphol Embryol. 2007;48(2):181–7.Google Scholar
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    Dezube BJ. Clinical presentation and natural history of AIDS-related Kaposi’s sarcoma. Hematol Oncol Clin North Am. 1996;10(5):1023–9.CrossRefGoogle Scholar
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    Cavallin LE, Goldschmidt-Clermont P, Mesri EA. Molecular and cellular mechanisms of KSHV oncogenesis of Kaposi’s sarcoma associated with HIV/AIDS. PLoS Pathog. 2014;10(7):e1004154.CrossRefGoogle Scholar
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    Tappero JW, Berger TG, Kaplan LD, Volberding PA, Kahn JO. Cryotherapy for cutaneous Kaposi’s sarcoma (KS) associated with acquired immune deficiency syndrome (AIDS): a phase II trial. J Acquir Immune Defic Syndr. 1991;4(9):839–46.CrossRefGoogle Scholar
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    Anglemyer A, Agrawal AK, Rutherford GW. Treatment of Kaposi sarcoma in children with HIV-1 infection. Cochrane Database Syst Rev. 2014;(1):CD009826.Google Scholar

Copyright information

© Springer Nature Switzerland AG 2020

Authors and Affiliations

  • Tangie Ngek Larry
    • 1
  • Derrick Tembi Efie
    • 2
    • 3
  1. 1.Faculty of Medicine and Biomedical SciencesUniversity of Yaounde 1YaoundeCameroon
  2. 2.Tokombere District HospitalTokombereCameroon
  3. 3.Health and Human Development Research NetworkDoualaCameroon

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