Fever and Cervical Lymphadenopathy

  • Berenise Gamez-Gonzalez
  • Marco Antonio Yamazaki-Nakashimada


  • Kawasaki disease (KD) should be considered in the differential diagnosis of any prolonged or unexplained fever in childhood

  • Cervical lymphadenopathy is an uncommon clinical feature in KD, but can be the only initial clinical finding

  • When a patient with KD develops new fever within 36 h after the last dose of intravenous immunoglobulin (IVIG) infusion, IVIG resistance has to be considered

  • Macrophage activation syndrome is a potential complication of KD

  • Treatment of refractory KD includes repeated IVIG infusions with infliximab and/or corticosteroids


Kawasaki disease Intravenous immunoglobulin Cervical lymphadenopathy 


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Copyright information

© Springer Nature Switzerland AG 2020

Authors and Affiliations

  • Berenise Gamez-Gonzalez
    • 1
  • Marco Antonio Yamazaki-Nakashimada
    • 2
  1. 1.Hospital Infantil de Especialidades de ChihuahuaChihuahuaMexico
  2. 2.Clinical Immunology DepartmentInstituto Nacional de PediatríaMexico CityMexico

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