Recurrent Interstitial Keratitis and Audiovestibular Dysfunction

  • Kristina A. Dzhuma
  • Oleg B. Iaremenko
  • Maksym I. Situkho


  • Cogan’s syndrome is a rare presumed autoimmune disorder characterized by non-syphilitic interstitial keratitis and Meniere’s syndrome-like audiovestibular dysfunction

  • Patients exhibiting hearing loss should undergo imaging studies as part of their initial evaluation

  • Important differential diagnoses include: Wegener’s granulomatosis, giant cell arteritis, Takayasu arteritis, sarcoidosis, rheumatoid arthritis, and Ménière’s disease with ocular inflammation

  • High dose systemic corticosteroid treatment should be initiated. A favourable response expected in 82% of patients


Cogan’s syndrome Interstitial keratitis Audiovestibular Audiovestibular dysfunction 


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Copyright information

© Springer Nature Switzerland AG 2020

Authors and Affiliations

  • Kristina A. Dzhuma
    • 1
  • Oleg B. Iaremenko
    • 2
  • Maksym I. Situkho
    • 3
  1. 1.Bogomolets National Medical University, National Specialized Children’s HospitalKyivUkraine
  2. 2.Department of Internal MedicineBogomolets National Medical UniversityKyivUkraine
  3. 3.O. Kolomijchenko Otolaryngology InstituteKyivUkraine

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