Adolescents and adults with autism spectrum disorder (ASD) are at high risk of developing mood disorder and so depressive disorder.
Depressive syndrome could be related to bipolar disorder, adjustment disorder, major depression or a medical disease.
Suicide has a higher prevalence in ASD individuals than in general population.
Clinicians must detect depressive symptoms that could be misdiagnosed as an autistic social withdrawal.
In intellectual disability, a specific attention must be directed to behavioural symptoms that could be a clinical equivalent to depressive symptoms.
Parents of ASD individuals are at heightened risk for depression compared to parents of typically developing children and children with other health and developmental disorder.
Social support, psychotherapy and social skill training may improve social withdrawal and reduce the risk of depressive disorder and suicide.
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