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Gut Microbiota and Aging

  • Daria A. KashtanovaEmail author
  • Olga N. Tkacheva
  • Irina D. Strazhesko
  • Ekaterina N. Dudinskaya
  • Yu V. Kotovskaya
  • A. S. Popenko
  • A. V. Tyaht
  • D. G. Alexeev
Chapter
Part of the Healthy Ageing and Longevity book series (HAL, volume 10)

Abstract

Gut microbiota is an up-to date theme that is widely studied. Now it is obvious that microbiota could be considered as one of the factors affecting aging process. Some reports suggested the potential mechanisms by which gut microbes may influence human health span. Aging-related conditions are accompanied by decline in immune system functioning and low-grade inflammation, and our microbes play a certain role in these processes. Gut microbiota composition changes during the aging process may indicate a more pronounced aging-related health loss.

Keywords

Microbiome Gut microbiota Longevity Butyrate Aging-associated diseases Short-chain fatty acids Low-grade inflammation Inflammaging Lipopolysaccharide 

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Copyright information

© Springer Nature Switzerland AG 2019

Authors and Affiliations

  • Daria A. Kashtanova
    • 1
    Email author
  • Olga N. Tkacheva
    • 1
  • Irina D. Strazhesko
    • 2
  • Ekaterina N. Dudinskaya
    • 1
  • Yu V. Kotovskaya
    • 1
  • A. S. Popenko
    • 3
  • A. V. Tyaht
    • 3
  • D. G. Alexeev
    • 3
  1. 1.Russian Clinical Research Center for Gerontology, Pirogov Russian National Research Medical UniversityMoscowRussia
  2. 2.Medical Scientific and Educational Center, Lomonosov Moscow State UniversityMoscowRussia
  3. 3.Atlas Health Europe LimitedLondonUK

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