Introduction to Tissue Engineering in Oral and Maxillofacial Surgery

  • Riitta Seppänen-KaijansinkkoEmail author


Tissue engineering (TE) has been considered as a third treatment modality complementing medicine and surgery. Its aim is to replace lost tissue, whether it is caused by congenital defect(s), trauma, or surgery. Langer and Vacanti, in 1993, determined tissue engineering as an “interdisciplinary field that applies the principles of engineering and the life sciences toward the development of biological substitutes that restore, maintain, or improve tissue function.” They published this definition in Science in 1993 [1]. Today it is a rapidly growing field of research expanding to all disciplines in medicine. Currently, it is possible to engineer both hard and soft tissues in oral and maxillofacial surgery.


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    Langer R, Vacanti JP. Tissue engineering. Science. 1993;260(5110):920–6.CrossRefGoogle Scholar
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    Martin I, Wendt D, Heberer M. The role of bioreactors in tissue engineering. Trends Biotechnol. 2004;22(2):80–6.CrossRefGoogle Scholar

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© Springer Nature Switzerland AG 2019

Authors and Affiliations

  1. 1.Department of Oral and Maxillofacial DiseasesUniversity of Helsinki and Helsinki University HospitalHelsinkiFinland

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