Role of Heat Shock Proteins in Brain Tumors
Heat shock proteins (HSP) constitute a major focus of cancer research. HSP have been found to be elevated in many human cancers and their expression has been related to patients’ prognosis. GBM is the most common primary malignant brain tumor with dismal prognosis. HSP have attracted a major interest as important anti-cancer targets since they have been implicated in glioma growth, invasion, angiogenesis and resistance to treatment. HSP inhibitors and vaccines are currently tested as new agents for brain tumors treatment.
KeywordsBrain tumor Glioma Heat shock proteins Inhibitors Medulloblastoma Vaccines
Heat shock protein
Heat shock protein-peptide complex-96
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