Cardiac Contractility

  • Fotios G. PitoulisEmail author
  • Pieter P. de Tombe
Part of the Learning Materials in Biosciences book series (LMB)


This chapter will equip you with an understanding of the determinants of cardiac contractility and the changes observed in these within the context of heart failure. We will begin by discussing the fundamentals of cardiac output, the effects of preload and afterload on ventricular function, and their clinical significance.


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Copyright information

© Springer Nature Switzerland AG 2019

Authors and Affiliations

  1. 1.National Heart and Lung Institute, Myocardial Function, Imperial College LondonLondonUK
  2. 2.Department of Physiology and BiophysicsCollege of Medicine, University of IllinoisChicagoUSA

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