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Mast Cells in Tumor Fate

  • Domenico RibattiEmail author
Chapter

Abstract

It is now well documented that neoplastic cells are influenced by their microenvironment and viceversa. The specific organ microenvironment determines the extent of cancer cell proliferation, angiogenesis, invasion and survival.

References

  1. Aaltomaa S, Lipponen P, Papinaho S et al (1993) Mast cells in breast cancer. Anticancer Res 13:785–788PubMedGoogle Scholar
  2. Baram D, Vaday G, Salamon P et al (2001) Human mast cells release metalloproteinase-9 on contact with activated T cells: juxtacrine regulation by TNF-alpha. J Immunol 167:4008–4016CrossRefGoogle Scholar
  3. Bingle L, Brown NJ, Lewis CE (2002) The role of tumor associated macrophages in tumor progression: implications for new anticancer therapies. J Pathol 196:254–265CrossRefGoogle Scholar
  4. Caplan RM (1963) The natural course of urticaria pigmentosa. Arch Dermatol 87:146–157CrossRefGoogle Scholar
  5. Chan JK, Magistris A, Loizzi V et al (2005) Mast cell density, angiogenesis, blood clotting, and prognosis in women with advanced ovarian cancer. Gynecol Oncol 99:20–25CrossRefGoogle Scholar
  6. Conti P, Pang X, Boucher W et al (1997) Impact of rantes and MCP-1 chemokines on in vivo basohilic mast cell recruitment in rat skin injection model and their role in modifying the protein and mrna levels for histidine decarboxylase. Blood 89:4120–4127PubMedGoogle Scholar
  7. Dabbous M, Walker R, Haney L et al (1986) Mast cells and matrix degradation at sites of tumor invasion in rat mammary adenocarcinoma. Br J Cancer 54:459–465CrossRefGoogle Scholar
  8. Dabiri S, Huntsman D, Makretsov N et al (2004) The presence of stromal mast cells identifies a subset of invasive breast cancers with a favorable prognosis. Mod Pathol 17:690–695CrossRefGoogle Scholar
  9. Dave SS, Wright G, Than B et al (2004) Prediction of survival in follicular lymphoma based on molecular features of tumor-infilitrating immune cells. N Engl J Med 351:2159–2169CrossRefGoogle Scholar
  10. Fukushima N, Satoh T, Sano M et al (2001) Angiogenesis and mast cell in non hodgkin’s lymphoma; a strong correlation in angioimmunoblastic T-cell lymphoma. Leuk Lymphoma 42:709–720CrossRefGoogle Scholar
  11. Fukushima H, Ohsawa M, Ikura Y et al (2006) Mast cells in diffuse large B-cell lymphoma; their role in fibrosis. Histopathology 49:498–505CrossRefGoogle Scholar
  12. Gooch SJ, Lee AV, Yee D (1998) Interleukin 4 inhibits growth and induces apoptosis in human breast cancer cells. Cancer Res 58:4199–4205PubMedGoogle Scholar
  13. Gruber BL, Marchese MJ, Kaw R (1995) Angiogenic factors stimulate mast cell migration. Blood 86:2488–2493PubMedGoogle Scholar
  14. Guidolin D, Nico B, Crivellato E et al (2008) Tumoral mast cells exhibit a common spatial distribution. Cancer Lett 273:80–85CrossRefGoogle Scholar
  15. Hara M, Matsumori A, Ono K et al (1999) Mast cells cause apotosis of cardiomyocytes and proliferation of other intramyocardial cells in vitro. Circulation 100:1443–1449CrossRefGoogle Scholar
  16. He S, Walls AF (1998) Human mast cell chymase induces the accumulation of neutrophils, eosinophils and other inflammatory cells in vivo. Br J Pharmacol 125:1491–1500CrossRefGoogle Scholar
  17. Ho KL (1984) Ultrastructure of cerebellar capillary hemangioblastoma. II. Mast Cells and Angiogenesis. Acta Neuropathol 64:308–318CrossRefGoogle Scholar
  18. Iamaroon A, Pongsiriwet S, Jittidecharaks S et al (2003) Increase of mast cells and tumor angiogenesis in oral squamous cell carcinoma. J Oral Pathol Med 32:195–199CrossRefGoogle Scholar
  19. Jenkins DC, Charles IG, Thompson LL et al (1995) Role of nitric oxide in tumor growth. Proc Natl Acad Sci USA 92:4392–4396CrossRefGoogle Scholar
  20. Kankkunen JP, Harvima IT, Naukkarinen A (1997) Qunatitative analysis of tryptase and chymase containing mast cells in benign and malignant breast lesions. Int J Cancer 72:385–388CrossRefGoogle Scholar
  21. Leek RD, Lander RJ, Harris AL et al (1999) Necrosis correlates with high vascular density and focal macrophages infiltration in invasive carcinoma of the breast. Br J Cancer 79:991–995CrossRefGoogle Scholar
  22. Lennert K, Parwaresch MR (1979) Mast cells and mast cell neoplasia: a review. Histopathology 3:349–365CrossRefGoogle Scholar
  23. Liotta L, Kohn EC (2001) The microenvironment of the tumor-host interface. Nature 411:375–379CrossRefGoogle Scholar
  24. Maślińska D, Woźniak R, Kaliszek A et al (1999) Phenotype of mast cells in the brain tumor. Capillary Hemangioblastoma. Folia Neuropathol 37:138–142PubMedGoogle Scholar
  25. Molin D (2004) Bystander cells and prognosis in Hodgkin lymphoma. Review based on a doctoral thesis. Ups J Med Sci 109:179–228CrossRefGoogle Scholar
  26. Molin D, Edstrom A, Glimelius I et al (2002) Mast cell infilitration correlates with poor prognosis in hodgkin’s lymphoma. Br J Haematol 119:122–124CrossRefGoogle Scholar
  27. Nechushtan H, Razin E (2002) The function of MIFT and associated proteins in mast cells. Mol Immunol 38:1177–1180CrossRefGoogle Scholar
  28. Nonomura N, Takayama H, Nishimura K et al (2007) Decreased number of mast cells infiltrating into needle biopsy specimens leads to a better prognosis of prostate cancer. Br J Cancer 97:952–956CrossRefGoogle Scholar
  29. Ohno S, Inagawa H, Soma G et al (2002) Role of tumor-associated macrophage in malignant tumors: should the location of the infiltrated macrophages be taken into account during evaluation? Anticancer Res 22:4269–4275PubMedGoogle Scholar
  30. Park CC, Bissell MJ, Barcellos-Hoff MH (2000) The influence of the microenvironment on the malignant phenotype. Mol Med Today 6:324–329CrossRefGoogle Scholar
  31. Polajeva J, Sjosten AM, Lager N et al (2011) Mast cell accumulation in glioblastoma with a potential role for stem cell factor and chemokine CXCL12. PLoS ONE 6:e25222CrossRefGoogle Scholar
  32. Reszec J, Hermanowicz A, Rutkowski R et al (2013) Evaluation of mast cells and hypoxia inducible factor-1 expression in meningiomas of various grades in correlation with peritumoral brain edema. J Neurooncol 115:119–125CrossRefGoogle Scholar
  33. Rojas IG, Spencer ML, Martinez A et al (2005) Characterization of mast cell subpopulations in lip cancer. J Oral Pathol Med 34:268–273CrossRefGoogle Scholar
  34. Samoszuk M, Corwin M (2003) Mast cell inhibitor cromolyn increases blood clotting and hypoxia in murine breast cancer. Int J Cancer 107:159–163CrossRefGoogle Scholar
  35. Sharma VK, Agrawal AK, Pratarp VK et al (1992) Mast cell reactivity in lymphoma: a preliminary communication. Indian J Cancer 29:61–65PubMedGoogle Scholar
  36. Stack MS, Johnson DA (1994) Human mast cell tryptase activates single-chain urinary-type plasminogen activator (pro-urokinase). J Biol Chem 269:9416–9419PubMedGoogle Scholar
  37. Theoharides T, Conti P (2004) Mast cells: the jekyll and hyde of tumor growth. Trends Immunol 25:235–241CrossRefGoogle Scholar
  38. Theoharides TC, Kempuraj D, Tagen M et al (2007) Differential release of mast cell mediators and the pathogenesis of inflammation. Immunol Rev 217:65–78CrossRefGoogle Scholar
  39. Theoharides TC, Rozniecki JJ, Sahagian G et al (2008) Impact of stress and mast cells on brain metastases. J Neuroimmunol 205:1–7CrossRefGoogle Scholar
  40. Thoresen S, Tangen M, Hartveit F (1982) Mast cells in the axillary nodes of breast cancer patients. Diagn Histopathol 5:65–67PubMedGoogle Scholar
  41. Torunilhac O, Santos DD, Xu L et al (2006) Mast cells in waldenstrom’s macroglobulinemia support lymphoplasmacytic cell growth through CD154/CD40 signaling. Ann Oncol 17:1275–1282CrossRefGoogle Scholar
  42. Travis WD, Li CY, Yam LT et al (1988) Significance of systemic mast cell disease with associated hematologic disorders. Cancer 62:965–972CrossRefGoogle Scholar
  43. Welsh TJ, Green RH, Richardson D et al (2005) Macrophage and mast cell invasion of tumor cell islets confers a marked survival advantage in non-small-cell lung cancer. J Clin Oncol 23:8959–8967CrossRefGoogle Scholar

Copyright information

© Springer Nature Switzerland AG 2019

Authors and Affiliations

  1. 1.Department of Biomedical Sciences, Neurosciences and Sensory OrgansUniversity of BariBariItaly

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