Dynamic 18F-Fluoride Imaging
Diseases affecting bone metabolism involve a wide range of skeletal and soft tissue disorders. They may be grouped as osteoporosis, osteomalacia, hyperparathyroidism, Paget’s disease of bone, and developmental disorders of bone. Age-related osteoporosis alone affects about 28 million Americans, and the cost of caring for osteoporosis-related fractures has recently been estimated to be about $14.8 billion each year.
- 6.Sachpekidis C, Hillengass J, Goldschmidt H3, Wagner B, Haberkorn U, Kopka K, Dimitrakopoulou-Strauss A. Treatment response evaluation with 18F-FDG PET/CT and 18F-NaF PET/CT in multiple myeloma patients undergoing high-dose chemotherapy and autologous stem cell transplantation. Eur J Nucl Med Mol Imaging. 2017;44(1):50–62.CrossRefGoogle Scholar
- 7.Simoncic U, Perlman S, Liu G, Staab MJ, Straus JE, Jeraj R. Comparison of NaF and FDG PET/CT for assessment of treatment response in castration-resistant prostate cancers with osseous metastases. Clin Genitourin Cancer. 2015;13(1):e7–e17. https://doi.org/10.1016/j.clgc.2014.07.001.CrossRefPubMedGoogle Scholar
- 8.Jenkins NW, Talbott JF, Shah V, Pandit P, Seo Y, Dillon WP, Majumdar S. [18F]-sodium fluoride PET MR-based localization and quantification of bone turnover as a biomarker for facet joint-induced disability. AJNR Am J Neuroradiol. 2017;38(10):2028–31. https://doi.org/10.3174/ajnr.A5348.CrossRefPubMedPubMedCentralGoogle Scholar