18F-Sodium Fluoride Positron Emission Tomography/Computed Tomography Imaging of the Peripheral Vasculature

  • Maaz B. J. SyedEmail author
  • Jakub Kaczynski
  • David E. Newby
Part of the Clinicians’ Guides to Radionuclide Hybrid Imaging book series (CGRHI)


Vascular pathology poses a significant burden on global disease. Vessel calcification is a systemic phenomenon that affects multiple organ beds. Many of the processes leading to vascular calcification share immune-mediated pathways [1, 2]. Contemporary investigative techniques obtain excellent images of morphological features within the vascular system. Established anatomical imaging, such as catheter angiography, computed tomography and magnetic resonance imaging, can accurately visualise the lumen [3]. Advances in computed tomography and magnetic resonance imaging now allow for the non-invasive detection of certain high-risk plaque features [4, 5]. Ultrasound duplex assesses the flow-limiting potential of stenotic lesions to provide a functional measure of vascular disease. Morphological imaging techniques are the basis of modern vascular imaging.


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Copyright information

© Springer Nature Switzerland AG 2020

Authors and Affiliations

  • Maaz B. J. Syed
    • 1
    Email author
  • Jakub Kaczynski
    • 1
  • David E. Newby
    • 1
  1. 1.British Heart Foundation Department of Cardiovascular SciencesQueens Medical Research Institute, University of EdinburghEdinburghUK

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